Gastric GI stromal tumors (GISTs): the role of surgery in the era of targeted therapy

MC Heinrich, CL Corless - Journal of surgical oncology, 2005 - Wiley Online Library
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasm
arising in the stomach. These tumors were previously classified as smooth muscle tumors …

A new online dynamic nomogram: construction and validation of a predictive model for distant metastasis risk and prognosis in patients with gastrointestinal stromal …

H Wu, P Ding, J Wu, C Sun, H Guo, S Chen… - Journal of …, 2023 - Elsevier
Background Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the
digestive tract, among which patients with distant metastases tend to have a poor prognosis …

Risk stratification of patients diagnosed with gastrointestinal stromal tumor

H Joensuu - Human pathology, 2008 - Elsevier
Accurate risk stratification of gastrointestinal stromal tumors (GISTs) has become
increasingly important owing to emerging adjuvant systemic treatments. All GISTs have …

Deletions Affecting Codons 557-558 of the c-KIT Gene Indicate a Poor Prognosis in Patients With Completely Resected Gastrointestinal Stromal Tumors: A Study by …

J Martín, A Poveda, A Llombart-Bosch… - Journal of Clinical …, 2005 - ascopubs.org
Purpose To explore the prognostic value of mutations in c-KIT and PDGFR-α genes with
respect to relapse-free survival (RFS) in patients with gastrointestinal stromal tumors (GIST) …

Risk criteria and prognostic factors for predicting recurrences after resection of primary gastrointestinal stromal tumor

P Rutkowski, ZI Nowecki, W Michej… - Annals of surgical …, 2007 - Springer
Background The introduction of adjuvant imatinib in gastrointestinal stromal tumors (GISTs)
raised debate over the accuracy of National Institutes of Health risk criteria and the …

Surgical treatment of patients with initially inoperable and/or metastatic gastrointestinal stromal tumors (GIST) during therapy with imatinib mesylate

P Rutkowski, Z Nowecki, P Nyckowski… - Journal of surgical …, 2006 - Wiley Online Library
Background The aim of the study was to analyze the surgical possibilities of unresectable
and/or metastatic GIST CD117 (+) patients during imatinib treatment. Methods We analyzed …

Surgically managed gastrointestinal stromal tumors: a comparative and prognostic analysis

I Hassan, YN You, R Shyyan, EJ Dozois… - Annals of surgical …, 2008 - Springer
Background Tyrosine kinase inhibitors have been shown to have marked clinical efficacy in
patients with unresectable or metastatic gastrointestinal stromal tumors (GIST). We …

Gastrointestinal stromal tumors: correlation between symptoms at presentation, tumor location and prognostic factors in 47 consecutive patients

S Caterino, L Lorenzon, N Petrucciani… - World journal of surgical …, 2011 - Springer
Background Gastrointestinal stromal tumors (GIST) are mesenchymal tumors of the
gastrointestinal tract, usually kit-positive, that are believed to originate from interstitial cell of …

An audit of surgical management of gastrointestinal stromal tumours (GIST)

P Bucher, JF Egger, P Gervaz, F Ris… - European Journal of …, 2006 - Elsevier
AIM: To analyze GIST outcome after primary resection and to determine if a new grading
system could adequately predict there prognosis. METHODS: A retrospective review (1993 …

An evaluation of 2537 gastrointestinal stromal tumors for a proposed clinical staging system

CE Woodall, GN Brock, J Fan, JA Byam… - Archives of …, 2009 - jamanetwork.com
Hypothesis A gastrointestinal stromal tumor (GIST) staging system can be created with the
Surveillance, Epidemiology and End Results (SEER) database. Design A review of records …