YX Du, XP Chen - Clinical Pharmacology & Therapeutics, 2020 - Wiley Online Library
An outbreak of 2019‐nCoV infection has spread across the world. No specific antiviral drugs have been approved for the treatment of COVID‐2019. In addition to the recommended …
S Yavuz, S Ünal - Turkish journal of medical sciences, 2020 - journals.tubitak.gov.tr
Currently, there is not any specific effective antiviral treatment for COVID-19. Although most of the COVID-19 patients have mild or moderate courses, up to 5%-10% can have severe …
K Shiraki, T Daikoku - Pharmacology & therapeutics, 2020 - Elsevier
Favipiravir has been developed as an anti-influenza drug and licensed as an anti-influenza drug in Japan. Additionally, favipiravir is being stockpiled for 2 million people as a …
Y Furuta, T Komeno, T Nakamura - … of the Japan Academy, Series B, 2017 - jstage.jst.go.jp
Abstract Favipiravir (T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) is an anti-viral agent that selectively and potently inhibits the RNA-dependent RNA polymerase (RdRp) of RNA …
V Pilkington, T Pepperrell, A Hill - Journal of virus eradication, 2020 - Elsevier
Background Repurposing broad-spectrum antivirals is an immediate treatment opportunity for 2019 coronavirus disease (COVID-19). Favipiravir is an antiviral previously indicated for …
Favipiravir, also known as T-705, is an antiviral drug that has been approved in 2014 in Japan to treat pandemic influenza virus infections. The drug is converted intracellularly into …
E De Clercq - Chemistry–An Asian Journal, 2019 - Wiley Online Library
Eight different compounds, all nucleoside analogues, could presently be considered as potential drug candidates for the treatment of Ebola virus (EBOV) and/or other hemorrhagic …
Sir, A novel coronavirus, SARS-CoV-2, emerged in December 2019 in Wuhan, China, which is spreading far more rapidly than its predecessors, having already infected millions of …
The present work describes development of rapid, robust, sensitive and green spectrofluorimetric method for determination of favipiravir (FAV). Different factors affecting …