[HTML][HTML] How to fail with paired VNS therapy

SA Hays, RL Rennaker II, MP Kilgard - Brain stimulation, 2023 - Elsevier
Vagus nerve stimulation (VNS) has gained enormous traction as a promising bioelectronic
therapy. In particular, the delivery of VNS paired with training to promote neural changes has …

Noninvasive brain stimulation for neurorehabilitation in post-stroke patients

KP Li, JJ Wu, ZL Zhou, DS Xu, MX Zheng, XY Hua… - Brain Sciences, 2023 - mdpi.com
Characterized by high morbidity, mortality, and disability, stroke usually causes symptoms of
cerebral hypoxia due to a sudden blockage or rupture of brain vessels, and it seriously …

[HTML][HTML] Vagus nerve stimulation induces widespread cortical and behavioral activation

L Collins, L Boddington, PJ Steffan, D McCormick - Current Biology, 2021 - cell.com
Vagus nerve stimulation (VNS) is used for management of a variety of neurological
conditions, although the therapeutic mechanisms are not fully understood. Accumulating …

Quantified morphology of the cervical and subdiaphragmatic vagus nerves of human, pig, and rat

NA Pelot, GB Goldhagen, JE Cariello… - Frontiers in …, 2020 - frontiersin.org
It is necessary to understand the morphology of the vagus nerve (VN) to design and deliver
effective and selective vagus nerve stimulation (VNS) because nerve morphology influences …

Norepinephrine and serotonin are required for vagus nerve stimulation directed cortical plasticity

DR Hulsey, CM Shedd, SF Sarker, MP Kilgard… - Experimental …, 2019 - Elsevier
Vagus nerve stimulation (VNS) paired with forelimb training drives robust, specific
reorganization of movement representations in the motor cortex. This effect is hypothesized …

Enhancing plasticity in central networks improves motor and sensory recovery after nerve damage

EC Meyers, N Kasliwal, BR Solorzano, E Lai… - Nature …, 2019 - nature.com
Nerve damage can cause chronic, debilitating problems including loss of motor control and
paresthesia, and generates maladaptive neuroplasticity as central networks attempt to …

Effects of stimulus frequency, intensity, and sex on the autonomic response to transcutaneous vagus nerve stimulation

H Yokota, M Edama, R Hirabayashi, C Sekine… - Brain sciences, 2022 - mdpi.com
This study aimed to determine how transcutaneous vagus nerve stimulation (tVNS) alters
autonomic nervous activity by comparing the effects of different tVNS frequencies and …

Rapid effects of vagus nerve stimulation on sensory processing through activation of neuromodulatory systems

C Rodenkirch, JB Carmel, Q Wang - Frontiers in neuroscience, 2022 - frontiersin.org
After sensory information is encoded into neural signals at the periphery, it is processed
through multiple brain regions before perception occurs (ie, sensory processing). Recent …

Optimizing dosing of vagus nerve stimulation for stroke recovery

DT Pruitt, TT Danaphongse, M Lutchman… - Translational stroke …, 2021 - Springer
Vagus nerve stimulation (VNS) paired with rehabilitative training enhances recovery of
function in models of stroke and is currently under investigation for use in chronic stroke …

[HTML][HTML] Characterization of vagus nerve stimulation-induced pupillary responses in epileptic patients

S Vespa, L Stumpp, G Liberati, J Delbeke, A Nonclercq… - Brain stimulation, 2022 - Elsevier
Background Modulation of the locus coeruleus (LC)-noradrenergic system is a key
mechanism of vagus nerve stimulation (VNS). Activation of the LC produces pupil dilation …