Lung diseases are the leading cause of mortality worldwide. The currently available
therapies are not sufficient, leading to the urgent need for new therapies with sustained anti …

Mycobacterium tuberculosis (Mtb) is an extremely successful intracellular pathogen that
causes tuberculosis (TB), which remains the leading infectious cause of human death. The …

Autophagy has broad functions in immunity, ranging from cell-autonomous defence to
coordination of complex multicellular immune responses. The successful resolution of …

Phagocytosis is a fundamental process of cells to capture and ingest foreign particles. Small
unicellular organisms such as free-living amoeba use this process to acquire food. In …

Pathogenic bacteria cause various infections worldwide, especially in immunocompromised
and other susceptible individuals, and are also associated with high infant mortality rates in …

Upon infection, mycobacteria, such as Mycobacterium tuberculosis (Mtb) and
nontuberculous mycobacteria (NTM), are recognized by host innate immune cells, triggering …

Innate immune responses are primary, relatively limited, and specific responses to
numerous pathogens and toxic molecules. Protein expression involved in these innate …

Autophagy is a well-conserved lysosomal degradation pathway that plays key roles in
bacterial infections. One of the most studied is probably xenophagy, the selective capture …

Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) kills millions every year, and
there is urgent need to develop novel anti-TB agents due to the fast-growing of drug …

Mycobacterium tuberculosis (Mtb) is the pathogen that causes tuberculosis (TB), a leading
infectious disease of humans worldwide. One of the main histopathological hallmarks of TB …