Modeling and simulation of genetic regulatory systems: a literature review

H De Jong - Journal of computational biology, 2002 - liebertpub.com
In order to understand the functioning of organisms on the molecular level, we need to know
which genes are expressed, when and where in the organism, and to which extent. The …

A review of symbolic analysis of experimental data

CS Daw, CEA Finney, ER Tracy - Review of Scientific instruments, 2003 - pubs.aip.org
This review covers the group of data-analysis techniques collectively referred to as
symbolization or symbolic time-series analysis. Symbolization involves transformation of raw …

Qualitative simulation of genetic regulatory networks using piecewise-linear models

H De Jong, JL Gouzé, C Hernandez, M Page… - Bulletin of mathematical …, 2004 - Elsevier
In order to cope with the large amounts of data that have become available in genomics,
mathematical tools for the analysis of networks of interactions between genes, proteins, and …

Piecewise-linear models of genetic regulatory networks: equilibria and their stability

R Casey, H Jong, JL Gouzé - Journal of mathematical biology, 2006 - Springer
A formalism based on piecewise-linear (PL) differential equations, originally due to Glass
and Kauffman, has been shown to be well-suited to modelling genetic regulatory networks …

[图书][B] Control of complex systems: Structural constraints and uncertainty

A Zecevic, DD Siljak - 2010 - books.google.com
" Control of Complex Systems: Structural Constraints and Uncertainty" focuses on control
design under information structure constraints, with a particular emphasis on large-scale …

A framework for three-dimensional simulation of morphogenesis

TM Cickovski, C Huang, R Chaturvedi… - IEEE/ACM …, 2005 - ieeexplore.ieee.org
We present COMPUCELL3D, a software framework for three-dimensional simulation of
morphogenesis in different organisms. COMPUCELL3D employs biologically relevant …

Complexity analysis of stride interval time series by threshold dependent symbolic entropy

W Aziz, M Arif - European journal of applied physiology, 2006 - Springer
The stride interval of human gait fluctuates in complex fashion. It reflects the rhythm of the
locomotor system. The temporal fluctuations in the stride interval provide us a non-invasive …

[PDF][PDF] A description of dynamical graphs associated to elementary regulatory circuits

E Remy, B Mossé, C Chaouiya, D Thieffry - Bioinformatics-Oxford, 2003 - researchgate.net
The biological and dynamical importance of feedback circuits in regulatory graphs has often
been emphasized. The work presented here aims at completly describing the dynamics of …

Limit cycles in models of circular gene networks regulated by negative feedback loops

VA Likhoshvai, VP Golubyatnikov, TM Khlebodarova - BMC bioinformatics, 2020 - Springer
Background The regulatory feedback loops that present in structural and functional
organization of molecular-genetic systems and the phenomenon of the regulatory signal …

Discrete time piecewise affine models of genetic regulatory networks

R Coutinho, B Fernandez, R Lima… - Journal of Mathematical …, 2006 - Springer
We introduce simple models of genetic regulatory networks and we proceed to the
mathematical analysis of their dynamics. The models are discrete time dynamical systems …