Buprenorphine is a Schedule III opioid analgesic with unique pharmacodynamic and
pharmacokinetic properties that may be preferable to those of Schedule II full μ-opioid …

Objective: Opioid use disorder (OUD) in the United States has surged, with an estimated 2.5
million needing treatment. The aim of this article is to provide a clinical overview of the key …

The term 'opioids' refers to both the natural compounds ('opiates') which are extracted from
the opium poppy plant (Papaver somniferum) and their semi-synthetic and synthetic …

Objective: A recent, global, increase in the use of opioids including the prescribing, highly
potent, fentanyl has been recorded. Due its current popularity and the potential lethal …

With the opioid crisis in North America, opioid addiction has come in the spotlight and
reveals the weakness of the current treatments. Two main opioid substitution therapies …

A simple-to-use device to measure drugs in saliva, blood plasma, and whole blood for point-
of-care analysis and treatment of overdose patients has been investigated. A rudimentary …

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are being increasingly
employed as a part of multimodal non-opioid strategies to treat postoperative pain. In the …

Chronic pain is one of the most common reasons adults seek medical care and is often
managed with opioid analgesics; however, opioids may cause respiratory depression by …

Adolescence is the transitional period between childhood and adulthood and a critical
period in brain development. Adolescence in humans is also associated with increased …

Abstract Purpose of Review The opioid epidemic has been responsible for significant
morbidity and mortality in the USA and worldwide. As a result, it is essential to recognize the …