An erythrocyte-centric view on the MFSD2B sphingosine-1-phosphate transporter

S Ghaderi, B Levkau - Pharmacology & Therapeutics, 2023 - Elsevier
MFSD2B has been identified as the exclusive sphingosine-1-phosphate (S1P) transporter in
red blood cells (RBC) and platelets. MFSD2B-mediated S1P export from platelets is required …

Magnetophoresis in microfluidic lab: Recent advance

P Su, C Ren, Y Fu, J Guo, J Guo, Q Yuan - Sensors and Actuators A …, 2021 - Elsevier
Microfluidic technology has shown great application prospects in biochemical analysis, drug
delivery, disease diagnosis, and other fields. Magnetophoresis is an effective means to …

Reduced platelet forces underlie impaired hemostasis in mouse models of MYH9-related disease

J Baumann, L Sachs, O Otto, I Schoen, P Nestler… - Science …, 2022 - science.org
MYH9-related disease patients with mutations in the contractile protein nonmuscle myosin
heavy chain IIA display, among others, macrothrombocytopenia and a mild-to-moderate …

MYH9 is crucial for stem cell-like properties in non-small cell lung cancer by activating mTOR signaling

M Chen, LX Sun, L Yu, J Liu, LC Sun, ZH Yang… - Cell Death …, 2021 - nature.com
The fatality rate of non-small cell lung cancer (NSCLC) has been high due to the existence
of cancer stem cells (CSCs). Non-muscle myosin heavy chain 9 (MYH9) can promote the …

[HTML][HTML] Ruscogenin alleviates LPS-triggered pulmonary endothelial barrier dysfunction through targeting NMMHC IIA to modulate TLR4 signaling

Y Wu, X Yu, Y Wang, Y Huang, J Tang, S Gong… - … Pharmaceutica Sinica B, 2022 - Elsevier
Pulmonary endothelial barrier dysfunction is a hallmark of clinical pulmonary edema and
contributes to the development of acute lung injury (ALI). Here we reported that ruscogenin …

[HTML][HTML] MYH9: A key protein involved in tumor progression and virus-related diseases

Q Liu, C Cheng, J Huang, W Yan, Y Wen, Z Liu… - Biomedicine & …, 2024 - Elsevier
The myosin heavy chain 9 (MYH9) gene encodes the heavy chain of non-muscle myosin IIA
(NMIIA), which belongs to the myosin II subfamily of actin-based molecular motors. Previous …

Non-uniform distribution of myosin-mediated forces governs red blood cell membrane curvature through tension modulation

H Alimohamadi, AS Smith, RB Nowak… - PLoS computational …, 2020 - journals.plos.org
The biconcave disk shape of the mammalian red blood cell (RBC) is unique to the RBC and
is vital for its circulatory function. Due to the absence of a transcellular cytoskeleton, RBC …

MYH9-related disease: it does exist, may be more frequent than you think and requires specific therapy

R Fernandez-Prado, SM Carriazo-Julio… - Clinical kidney …, 2019 - academic.oup.com
In this issue of ckj, Tabibzadeh et al. report one of the largest series of patients with MYH9
mutations and kidney disease. The cardinal manifestation of MYH9-related disease is …

Identification of Transferrin Receptor 1 (TfR1) Overexpressed in Lung Cancer Cells, and Internalization of Magnetic Au-CoFe2O4 Core-Shell Nanoparticles …

R Villalobos-Manzo, E Ríos-Castro… - Pharmaceutics, 2022 - mdpi.com
Lung cancer is, currently, one of the main malignancies causing deaths worldwide. To date,
early prognostic and diagnostic markers for small cell lung cancer (SCLC) have not been …

A familial case of MYH9 gene mutation associated with multiple functional and structural platelet abnormalities

SI Safiullina, NG Evtugina, IA Andrianova… - Scientific Reports, 2022 - nature.com
Mutations in the MYH9 gene result in macrothrombocytopenia often associated with
hemorrhages. Here, we studied the function and structure of platelets in three family …