Cardiovascular disease (CVD) is a major contributor to increasing morbidity and mortality
worldwide and seriously threatens human health and life. Cardiomyocyte death is …

Significance: The multifactorial nature of the mechanisms implicated in cancer development
still represents a major issue for the success of established antitumor therapies. The …

The development of drug resistance remains a major challenge in cancer treatment.
Ferroptosis, a unique type of regulated cell death, plays a pivotal role in inhibiting tumour …

Object In this study, we aimed to elucidate the role of LUCAT1, a recently identified lncRNA,
in ferroptosis within the context of bladder cancer (BC). Methods Through a comprehensive …

The morbidity and mortality rates of cardiovascular diseases (CVDs) are increasing; thus,
they impose substantial health and economic burdens worldwide, and effective interventions …

Cerebral ischemic stroke and glioma are the two leading causes of patient mortality globally.
Despite physiological variations, 1 in 10 people who have an ischemic stroke go on to …

Background Cuproptosis, a novel form of programmed cell death, plays an essential role in
various cancers. However, studies of the function of cuproptosis lncRNAs (CRLs) in …

Homocysteine (Hcy) is a metabolic intermediate product derived from methionine.
Hyperhomocysteinemia is a condition associated with various diseases. Hcy is recognized …

Objective: MicroRNA-143 (miR-145) has shown promising tumor-suppressive effects in
different types of cancer and could potentially act as a tumor suppressor in liver cancer. To …

A circular RNA (circRNA) is a non-coding RNA (ncRNA) derived from reverse splicing from
pre-mRNA and is characterized by the absence of a cap structure at the 5′ end and a poly …