[HTML][HTML] Broad targeting of resistance to apoptosis in cancer

RM Mohammad, I Muqbil, L Lowe, C Yedjou… - Seminars in cancer …, 2015 - Elsevier
Apoptosis or programmed cell death is natural way of removing aged cells from the body.
Most of the anti-cancer therapies trigger apoptosis induction and related cell death networks …

The relationship between autophagy and the immune system and its applications for tumor immunotherapy

GM Jiang, Y Tan, H Wang, L Peng, HT Chen, XJ Meng… - Molecular cancer, 2019 - Springer
Autophagy is a genetically well-controlled cellular process that is tightly controlled by a set of
core genes, including the family of autophagy-related genes (ATG). Autophagy is a “double …

Different types of cell death and their shift in shaping disease

S Shen, Y Shao, C Li - Cell death discovery, 2023 - nature.com
Cell death is the irreversible stop of life. It is also the basic physiological process of all
organisms which involved in the embryonic development, organ maintenance and …

[HTML][HTML] Autophagy and apoptosis dysfunction in neurodegenerative disorders

S Ghavami, S Shojaei, B Yeganeh, SR Ande… - Progress in …, 2014 - Elsevier
Autophagy and apoptosis are basic physiologic processes contributing to the maintenance
of cellular homeostasis. Autophagy encompasses pathways that target long-lived cytosolic …

Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells

E Ooko, MEM Saeed, O Kadioglu, S Sarvi, M Colak… - Phytomedicine, 2015 - Elsevier
Background Apoptosis and other forms of cell death have been intensively investigated in
the past years to explain the mode of action of synthetic anticancer drugs and natural …

Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis

H Gali-Muhtasib, R Hmadi, M Kareh, R Tohme… - Apoptosis, 2015 - Springer
Despite remarkable progress in the discovery and development of novel cancer
therapeutics, cancer remains the second leading cause of death in the world. For many …

[HTML][HTML] Mitochondrial channels: ion fluxes and more

I Szabo, M Zoratti - Physiological reviews, 2014 - journals.physiology.org
The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Peptide-based cancer therapy: opportunity and challenge

D Wu, Y Gao, Y Qi, L Chen, Y Ma, Y Li - Cancer letters, 2014 - Elsevier
Cancer is one of the leading causes of death worldwide. Conventional cancer therapies
mainly focus on mass cell killing without high specificity and often cause severe side effects …

Pancreatic beta cell death: novel potential mechanisms in diabetes therapy

J Rojas, V Bermudez, J Palmar… - Journal of Diabetes …, 2018 - Wiley Online Library
Purpose of Review. Describing the diverse molecular mechanisms (particularly
immunological) involved in the death of the pancreatic beta cell in type 1 and type 2 …

Targeting ROS-mediated crosstalk between autophagy and apoptosis in cancer

L Gao, J Loveless, C Shay, Y Teng - Reviews on new drug targets in age …, 2020 - Springer
The control of crosstalk between autophagy and apoptosis in tumor cells can remove a
critical barrier to comprehensive and efficacious treatment for cancer. Reactive oxygen …