Strategies for making high‐performance artificial spider silk fibers

B Schmuck, G Greco, TB Pessatti… - Advanced Functional …, 2024 - Wiley Online Library
Artificial spider silk is an attractive material for many technical applications since it is a
biobased fiber that can be produced under ambient conditions but still outcompetes …

Protein phase separation arising from intrinsic disorder: first-principles to bespoke applications

DM Shapiro, M Ney, SA Eghtesadi… - The Journal of Physical …, 2021 - ACS Publications
The phase separation of biomolecules has become the focus of intense research in the past
decade, with a growing body of research implicating this phenomenon in essentially all …

1000 spider silkomes: Linking sequences to silk physical properties

K Arakawa, N Kono, AD Malay, A Tateishi, N Ifuku… - Science …, 2022 - science.org
Spider silks are among the toughest known materials and thus provide models for
renewable, biodegradable, and sustainable biopolymers. However, the entirety of their …

Spider silk self-assembly via modular liquid-liquid phase separation and nanofibrillation

AD Malay, T Suzuki, T Katashima, N Kono… - Science …, 2020 - science.org
Spider silk fiber rapidly assembles from spidroin protein in soluble state via an incompletely
understood mechanism. Here, we present an integrated model for silk formation that …

Protein secondary structure in spider silk nanofibrils

Q Wang, P McArdle, SL Wang, RL Wilmington… - Nature …, 2022 - nature.com
Nanofibrils play a pivotal role in spider silk and are responsible for many of the impressive
properties of this unique natural material. However, little is known about the internal …

Identification and characterization of sericin5 reveals non-cocoon silk sericin components with high β-sheet content and adhesive strength

K Guo, X Zhang, D Zhao, L Qin, W Jiang, W Hu, X Liu… - Acta Biomaterialia, 2022 - Elsevier
Sericins are glue proteins on the surface of silk fibers. Four sericins have been characterized
in silkworm, namely sericin1 (Ser1), sericin2 (Ser2), sericin3 (Ser3), and sericin4 (Ser4). In …

How to define and study structural proteins as biopolymer materials

K Numata - Polymer Journal, 2020 - nature.com
Structural proteins, including silk fibroins, play an important role in shaping the skeletons
and structures of cells, tissues, and organisms. The amino acid sequences of structural …

[HTML][HTML] Ancient fibrous biomaterials from silkworm protein fibroin and spider silk blends: Biomechanical patterns

N Johari, A Khodaei, A Samadikuchaksaraei, RL Reis… - Acta Biomaterialia, 2022 - Elsevier
Silkworm silk protein fibroin and spider silk spidroin are known biocompatible and natural
biodegradable polymers in biomedical applications. The presence of β-sheets in silk fibroin …

Complexity of spider dragline silk

AD Malay, HC Craig, J Chen, NA Oktaviani… - …, 2022 - ACS Publications
The tiny spider makes dragline silk fibers with unbeatable toughness, all under the most
innocuous conditions. Scientists have persistently tried to emulate its natural silk spinning …

Orb-weaving spider Araneus ventricosus genome elucidates the spidroin gene catalogue

N Kono, H Nakamura, R Ohtoshi, DAP Moran… - Scientific reports, 2019 - nature.com
Members of the family Araneidae are common orb-weaving spiders, and they produce
several types of silks throughout their behaviors and lives, from reproduction to foraging …