The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

KATP channels are integral to the functions of many cells and tissues. The use of
electrophysiological methods has allowed for a detailed characterization of KATP channels …

In experimental studies in the dog, total proximal coronary artery occlusions of up to 15
minutes result in reversible injury, meaning that the myocytes survive this insult. The 15 …

Objective: We previously showed that brief intermittent ischemia applied during the onset of
reperfusion (ie, postconditioning) is cardioprotective in a canine model of ischemia …

On July 2–3, 1996, the National Heart, Lung, and Blood Institute sponsored a workshop in
Columbia, Md, entitled “The Medical and Cellular Implications of Myocardial Stunning …

In addition to their normal physiological role in ATP production and metabolism,
mitochondria exhibit a dark side mediated by the opening of a non-specific pore in the inner …

Recent studies indicate that, in addition to necrosis, apoptosis also plays a role in the
process of tissue damage after myocardial infarction, which has pathological and …

OBJECTIVES We sought to determine the relationship of delayed hyperenhancement by
contrast magnetic resonance imaging (MRI) to viable and nonviable myocardium within the …

Objectives A series of brief coronary artery reperfusions and reocclusions applied during the
early minutes of coronary artery reflow (“postconditioning”) attenuates reperfusion injury …

Spatiotemporal regulation of the activity of a vast array of intracellular proteins and signaling
pathways by reactive oxygen species (ROS) governs normal cardiovascular function …