[HTML][HTML] Advances and challenges in the treatment of esophageal cancer

S He, J Xu, X Liu, Y Zhen - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Esophageal cancer (EC) is one of the most common cancers with high morbidity and
mortality rates. EC includes two histological subtypes, namely esophageal squamous cell …

CD147 is a promising target of tumor progression and a prognostic biomarker

A Landras, C Reger de Moura, F Jouenne, C Lebbe… - Cancers, 2019 - mdpi.com
Microenvironment plays a crucial role in tumor development and progression. Cancer cells
modulate the tumor microenvironment, which also contribute to resistance to therapy …

Laparoscopic versus open gastrectomy for gastric cancer

F Zeng, L Chen, M Liao, B Chen, J Long, W Wu… - World journal of surgical …, 2020 - Springer
Background Compared with open gastrectomy (OG), laparoscopic gastrectomy (LG) for
gastric cancer has achieved rapid development and popularities in the past decades …

CD147 Promotes Tumorigenesis via Exosome-Mediated Signaling in Rhabdomyosarcoma

A Fahs, N Hussein, H Zalzali, F Ramadan… - Cells, 2022 - mdpi.com
Rhabdomyosarcoma (RMS) is an aggressive childhood soft-tissue tumor, with propensity for
local invasion and distant metastasis. Exosomes are secreted vesicles that mediate …

CD147-cyclophilin a interactions promote proliferation and survival of cutaneous T-cell lymphoma

M Sakamoto, T Miyagaki, H Kamijo, T Oka… - International Journal of …, 2021 - mdpi.com
CD147, a transmembrane glycoprotein that belongs to the immunoglobulin superfamily, and
cyclophilin A (CypA), one of the binding partners of CD147, are overexpressed in tumor cells …

BSG (CD147) serum level and genetic variants are associated with overall survival in acute myeloid leukaemia

P Łacina, A Butrym, E Turlej… - Journal of Clinical …, 2022 - mdpi.com
Basigin (BSG, CD147) is a multifunctional protein involved in cancer cell survival, mostly by
controlling lactate transport through its interaction with monocarboxylate transporters (MCTs) …

A lectin-based glycomic approach identifies FUT8 as a driver of radioresistance in oesophageal squamous cell carcinoma

L Shen, M Xia, X Deng, Q Ke, C Zhang, F Peng… - Cellular Oncology, 2020 - Springer
Purpose Radio-resistance is recognized as a main factor in the failure of radiotherapy in
oesophageal squamous cell carcinoma (ESCC). Aberrant cell surface glycosylation has …

Association between oral microflora and gastrointestinal tumors

X Li, S Zhu, T Zhang, X Chen - Oncology Reports, 2021 - spandidos-publications.com
The oral cavity contains the highest density and the most species of microorganisms
compared with other parts of the body. Recent studies have determined that the species and …

A chalcone inhibits the growth and metastasis of KYSE-4 esophageal cancer cells

J Chen, CY Kang, ZX Niu, HC Zhou… - Journal of …, 2020 - journals.sagepub.com
Objective To investigate the in vitro and in vivo anticancer effects of a chalcone against
KYSE-4 esophageal cancer cells. Methods A chalcone was synthesized via the molecular …

Downregulation of CyclophilinA/CD147 axis induces cell apoptosis and inhibits glioma aggressiveness

S Xu, C Hu, Z Xiao, C Luo, Z Liu - BioMed Research …, 2020 - Wiley Online Library
Gliomas are the most common primary tumors in the brain with poor prognosis. Previous
studies have detected high expression of Cyclophilin A (CyPA) and CD147, respectively, in …