[HTML][HTML] DNA nanotechnology as a tool to develop molecular tension probes for bio-sensing and bio-imaging applications: An up-to-date review

MMFA Baig, WF Lai, MF Akhtar, A Saleem… - Nano-Structures & Nano …, 2020 - Elsevier
DNA is known to be a life material that has been explored as an exciting biomaterial for bio-
sensing, bio-imaging, and analytical applications. The current review focuses on describing …

Elastic Network Model: A Coarse-Grained Approach to the Study of Biomolecular Dynamics

SW Park, BH Lee, MK Kim - Multiscale Science and Engineering, 2023 - Springer
Over the past several decades, biomolecular dynamics has been extensively investigated
through both theoretical and experimental approaches to uncover the general relationship …

[HTML][HTML] Exploring the robustness of DNA nanotubes framework for anticancer theranostics toward the 2D/3D clusters of hypopharyngeal respiratory tumor cells

MMFA Baig, J Ma, X Gao, MA Khan, A Ali… - International Journal of …, 2023 - Elsevier
This study aimed to develop a robust approach for the early diagnosis and treatment of
tumors. Short circular DNA nanotechnology synthesized a stiff and compact DNA nanotubes …

Self-assembly of multi-stranded RNA motifs into lattices and tubular structures

JM Stewart, HKK Subramanian… - Nucleic acids research, 2017 - academic.oup.com
Rational design of nucleic acid molecules yields self-assembling scaffolds with increasing
complexity, size and functionality. It is an open question whether design methods tailored to …

Charge neutralization drives the shape reconfiguration of DNA nanotubes

P Liu, Y Zhao, X Liu, J Sun, D Xu, Y Li, Q Li… - Angewandte …, 2018 - Wiley Online Library
Reconfiguration of membrane protein channels for gated transport is highly regulated under
physiological conditions. However, a mechanistic understanding of such channels remains …

[HTML][HTML] Synthesis of ligand functionalized ErbB-3 targeted novel DNA nano-threads loaded with the low dose of doxorubicin for efficient in vitro evaluation of the …

MMFA Baig, WF Lai, A Ahsan, M Jabeen… - Pharmaceutical …, 2020 - Springer
Abstract Purpose Doxorubicin (Dox) being a hydrophobic drug needs a unique carrier for
the effective encapsulation with uniformity in the aqueous dispersion, cell culture media and …

A mass weighted chemical elastic network model elucidates closed form domain motions in proteins

MH Kim, S Seo, JI Jeong, BJ Kim, WK Liu… - Protein …, 2013 - Wiley Online Library
An elastic network model (ENM), usually Cα coarse‐grained one, has been widely used to
study protein dynamics as an alternative to classical molecular dynamics simulation. This …

Ternary and senary representations using DNA double-crossover tiles

B Kim, S Jo, J Son, J Kim, MH Kim, SU Hwang… - …, 2014 - iopscience.iop.org
The information capacity of DNA double-crossover (DX) tiles was successfully increased
beyond a binary representation to higher base representations. By controlling the length and …

Development and functionalization of DNA nanostructures for biomedical applications

MMFA Baig, T Zou, P Neelakantan… - Journal of the Chinese …, 2021 - Wiley Online Library
Nanomaterials are excellent drug delivery systems, yet, they must be functionalized in a
manner compatible with the biological environment. Regarding delivery of the payloads, it is …

Vibrational characteristics of DNA nanostructures obtained through a mass-weighted chemical elastic network model

S Jo, J Son, BH Lee, SR Dugasani, SH Park, MK Kim - RSC advances, 2017 - pubs.rsc.org
Using the programmable and self-assembly characteristics of DNA, various DNA
nanostructures have been designed and synthesized for specific applications, such as …