Vitamin D (VitD) is a prohormone most noted for the regulation of calcium and phosphate
levels in circulation, and thus of bone metabolism. Inflammatory and immune cells not only …

Vitamin D deficiency has been associated with a wide range of diseases and multiple forms
of cancer including breast, colon, and prostate cancers. Relatively recent work has …

Vitamin D deficiency is an established risk factor for many autoimmune diseases and the
anti-inflammatory properties of vitamin D underscore its potential therapeutic value for these …

The role of diet in the pathogenesis of inflammatory bowel disease (IBD) remains an open
topic despite the advances in the understanding of the gastrointestinal pathophysiology …

The lumen of the gut hosts a plethora of microorganisms that participate in food assimilation,
inactivation of harmful particles and in vitamin synthesis. On the other hand, enteric flora, a …

Intestinal microbial flora, known as the second gene pool of the human body, play an
important role in immune function, nutrient uptake, and various activities of host cells, as well …

Vitamin D refers to a class of fat-soluble secosteroids often associated with their role in
absorption and metabolism of minerals such as calcium and phosphate. In recent years, our …

Osteopenia and osteoporosis are common features in inflammatory bowel disease (IBD),
comprising both Crohn's disease and ulcerative colitis. Moreover, Crohn's disease is …

Overall, patients have to deal with a cocktail of cytokines, present in their serum. The
combination of cytokines can affect bone cells differently compared to the effects of a single …

Matrix vesicles (MVs) provide the initial site for amorphous hydroxyapatite (HA) formation
within mineralizing osteoblasts. Although Na+/Ca2+ exchanger isoform‐3 (NCX3, SLC8A3) …