The continuous, in-depth exploration of the occurrence and development of cancer has
shown that immune cell dysfunction is closely associated with tumor progression and poor …

The incidence and mortality of digestive system-related cancers have always been high and
attributed to the heterogeneity and complexity of the immune microenvironment of the …

Tumor immunotherapy is a safe and effective strategy for precision medicine. However,
immunotherapy for most cancer cases still ends in failure, with the root causes of the …

Natural killer (NK) cells account for 25–50% of the total number of hepatic lymphocytes,
which implicates that NK cells play an important role in liver immunity. The frequencies of …

Cancer is a complex disease, and despite incredible progress over the last decade, it
remains the leading cause of death worldwide. Liver cancers, including hepatocellular …

Solid tumors consist of malignant and nonmalignant cells that together create the local tumor
microenvironment (TME). Additionally, the TME is characterized by the expression of …

Natural killer (NK) cells are innate immune cells which play a key role in shaping the
immune response against cancer. Initially hailed for their potential to recognise and …

Idiopathic pulmonary fibrosis (IPF) is a fibrotic age-related chronic lung disease
characterized by the accumulation of senescent cells. Whether impaired immune response …

Simultaneous measurement of multiple modalities in single-cell analysis, represented by
CITE-seq, is a promising approach to link transcriptional changes to cellular phenotype and …

Hepatocellular carcinoma (HCC) is a common and deadly cancer worldwide. Many factors
contribute to mortality and place an individual at high risk of developing HCC, including viral …