Antiretroviral therapy (ART) inhibits HIV replication but is not curative. During ART, the
integrated HIV genome persists indefinitely within CD4+ T cells and perhaps other cells …

Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a
global population of more than 35 million people living with HIV, there is intense interest in …

Importance New data and therapeutic options warrant updated recommendations for the use
of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults. Objective To …

HIV DNA is a marker of HIV persistence that predicts HIV progression and remission, but its
kinetics in early acute HIV infection (AHI) is poorly understood. We longitudinally measured …

SUMMARY HIV-1 DNA persists in infected cells despite combined antiretroviral therapy
(cART), forming viral reservoirs. Recent trials of strategies targeting latent HIV reservoirs …

Understanding the complexity of the long-lived HIV reservoir during antiretroviral therapy
(ART) remains a considerable impediment in research towards a cure for HIV. To address …

Despite our ability to suppress HIV-1 replication indefinitely in people on optimal combined
antiretroviral therapy (cART), HIV-1 persists as a stably integrated and replication-competent …

9 years since the report of a cure for HIV after CC chemokine receptor type 5 Δ32 stem cell
transplantation, no other case of HIV cure has been reported, despite much research …

Methods We conducted a scoping review [28] synthesizing the most recent literature on
clinical and public health implications of widespread AHI detection and treatment. This …

HIV remission can be achieved in some people, called post-treatment HIV controllers, after
antiretroviral treatment discontinuation. Treatment initiation close to the time of infection was …