Members of the protein superfamily of small guanosine triphosphatases, also known as
small GTPases, small G-proteins, or the Ras superfamily, are involved in nearly every aspect …

The correct wiring of neuronal circuits depends on outgrowth and guidance of neuronal
processes during development. In the past two decades, great progress has been made in …

Ciliogenesis requires the removal of CP110 from the mother centriole; actin dynamics also
influence ciliation, at least partly by affecting the centrosomal accumulation of ciliogenic …

The silk gland of the domesticated silkworm Bombyx mori, is a remarkable organ that
produces vast amounts of silk with exceptional properties. Little is known about which silk …

The WAVE regulatory complex (WRC), composed of five components—Cyfip1/Sra1,
WAVE/Scar, Abi, Nap1/Nckap1, and Brk1/HSPC300—is essential for proper actin …

The mechanisms linking guidance receptors to cytoskeletal dynamics in the growth cone
during axon extension remain mysterious. The Rho-family GTPases Rac and CDC-42 are …

Two decades after the first report of the plant homolog of the Receptor for Activated C Kinase
1 (RACK1) in cultured tobacco BY2 cells, a significant advancement has been made in the …

FMRP is an RNA-binding protein that represses the translation of specific mRNAs. In
neurons, its depletion determines the exaggerated translation of mRNAs leading to dendritic …

Autism spectrum disorder (ASD) is a neurodevelopmental condition with onset in early
childhood, still diagnosed only through clinical observation due to the lack of laboratory …

Among the genetic factors playing a key role in the etiology of intellectual disabilities (IDs)
and autism spectrum disorders (ASDs), several encode RNA-binding proteins (RBPs). In this …