Dendritic spines shape analysis—classification or clusterization? Perspective

E Pchitskaya, I Bezprozvanny - Frontiers in synaptic neuroscience, 2020 - frontiersin.org
Dendritic spines are small protrusions from the dendrite membrane, where contact with
neighboring axons is formed in order to receive synaptic input. Changes in size, shape, and …

Prophylactic ketamine treatment promotes resilience to chronic stress and accelerates recovery: correlation with changes in synaptic plasticity in the CA3 subregion of …

A Krzystyniak, E Baczynska, M Magnowska… - International Journal of …, 2019 - mdpi.com
Ketamine is an N-methyl-d-aspartate receptor antagonist that has gained wide attention as a
potent antidepressant. It has also been recently reported to have prophylactic effects in …

Quantitative 3-D morphometric analysis of individual dendritic spines

S Basu, PK Saha, M Roszkowska, M Magnowska… - Scientific reports, 2018 - nature.com
The observation and analysis of dendritic spines morphological changes poses a major
challenge in neuroscience studies. The alterations of their density and/or morphology are …

An interactive time series image analysis software for dendritic spines

AÖ Argunşah, E Erdil, MU Ghani, Y Ramiro-Cortés… - Scientific reports, 2022 - nature.com
Live fluorescence imaging has demonstrated the dynamic nature of dendritic spines, with
changes in shape occurring both during development and in response to activity. The …

Deep-Fuzz: A synergistic integration of deep learning and fuzzy water flows for fine-grained nuclei segmentation in digital pathology

N Das, S Saha, M Nasipuri, S Basu, T Chakraborti - Plos one, 2023 - journals.plos.org
Robust semantic segmentation of tumour micro-environment is one of the major open
challenges in machine learning enabled computational pathology. Though deep learning …

Early-Occurring Dendritic Spines Alterations in Mouse Models of Alzheimer's Disease Inform on Primary Causes of Neurodegeneration

M Ammassari-Teule - Frontiers in Synaptic Neuroscience, 2020 - frontiersin.org
The consensus that synaptic failure is the earliest cause of cognitive deterioration in
Alzheimer's disease (AD) has initially led to investigate structural (dendritic spines) and …

Dendritic spine classification using shape and appearance features based on two-photon microscopy

MU Ghani, F Mesadi, SD Kanık, AÖ Argunşah… - Journal of neuroscience …, 2017 - Elsevier
Background Neuronal morphology and function are highly coupled. In particular, dendritic
spine morphology is strongly governed by the incoming neuronal activity. The first step …

3dSpAn: An interactive software for 3D segmentation and analysis of dendritic spines

N Das, E Baczynska, M Bijata, B Ruszczycki, A Zeug… - Neuroinformatics, 2022 - Springer
Three-dimensional segmentation and analysis of dendritic spine morphology involve two
major challenges: 1) how to segment individual spines from the dendrites and 2) how to …

An expert system to diagnose spinal disorders

SMS Dashti, SF Dashti - arXiv preprint arXiv:2302.03625, 2023 - arxiv.org
Objective: Until now, traditional invasive approaches have been the only means being
leveraged to diagnose spinal disorders. Traditional manual diagnostics require a high …

[HTML][HTML] Morphological and Functional Alterations in the CA1 Pyramidal Neurons of the Rat Hippocampus in the Chronic Phase of the Lithium–Pilocarpine Model of …

TY Postnikova, GP Diespirov, SL Malkin… - International Journal of …, 2024 - mdpi.com
Epilepsy is known to cause alterations in neural networks. However, many details of these
changes remain poorly understood. The objective of this study was to investigate changes in …