Hypoplastic myelodysplastic syndrome (hMDS) and aplastic anemia (AA) are rare
hematopoietic disorders characterized by pancytopenia with hypoplastic bone marrow (BM) …

Erythropoiesis is a process of enormous magnitude, with the average person generating two
to three million red cells every second. Erythroid progenitors start as large cells with large …

Myelodysplastic Syndromes (MDSs) affect the elderly and can progress to Acute Myeloid
Leukemia (AML). Epigenetic alterations including DNA methylation and chromatin …

Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematopoietic stem
cell disorders with maturation and differentiation defects exhibiting morphological dysplasia …

Anemia is a common symptom of hematological malignancies and red blood cell (RBC)
transfusion is the primary supportive treatment, with many patients becoming transfusion …

Myelodysplastic syndrome/neoplasm (MDS) comprises a group of heterogeneous
hematopoietic disorders that present with genetic mutations and/or cytogenetic changes …

Etiological factors involved in myelodysplastic syndrome (MDS) include immunologic,
oxidative stress and inflammatory factors, among others, and these are targets for …

Epigenetic dysregulation of cancer-associated genes has been identified to contribute to the
pathogenesis of myelodysplastic syndromes (MDS). However, few studies have elucidated …

Background miRNAs are small non-coding RNAs that regulate gene expression and are
linked to cancer development and progression. miRNA profiles are currently studied as new …

MiRNAs have been identified as participants in leukemogenesis by controlling several
cellular functions, such as differentiation, proliferation, and apoptosis. Their role in …