Ethanol-induced gastric ulcer in rats and intervention of tert-butylhydroquinone: involvement of Nrf2/HO-1 signalling pathway

Z Rahman, DK Dwivedi… - Human & Experimental …, 2020 - journals.sagepub.com
Gastric ulcer (GU) is the most common health concern that occurs due to alcohol
consumption, smoking and physiological stress. Ethanol-induced GU in animal model …

Evaluation of anti-ulcer activity of the leaf extract of Osyris quadripartita Decne. (Santalaceae) in rats

M Abebaw, B Mishra, DA Gelayee - Journal of experimental …, 2017 - Taylor & Francis
Osyris quadripartita (OQ) Salzm. ex Decne. has been used to treat peptic ulcer disease in
Ethiopian folk medicine, but its efficacy has not been validated. The present study was …

Phenolic acids-rich fraction from Ficus drupacea leaves for the prevention and treatment of ethanol-induced gastric mucosal injury in rats

SM Bakry, AFA Naser, SIE Negoumy… - …, 2023 - Springer
Bioactivity-guided fractionation of F. drupacea Thunb. extract revealed that the water fraction
(FDWF) increased pH of the artificial gastric juice from 1.2 to 5.67±0.015. The …

Fish oil ameliorates ethanol-induced gastric injury in rat by modulating gene related to apoptosis

N Parham, K Rahimi, Z Ghotbeddin, MR Tabandeh - Scientific Reports, 2024 - nature.com
Gastric ulcers are a type of digestive disease that can severely affect a person's quality of
life. Our study aimed to investigate the effects of fish oil on ethanol-induced gastric ulcers in …

In vivo and In silico evidence of the protective properties of carvacrol against experimentally-induced gastric ulcer: Implication of antioxidant, anti-inflammatory, and …

AM Badr, NF El-Orabi, YF Mahran, AM Badr… - Chemico-Biological …, 2023 - Elsevier
Gastric ulcer is a serious disease that affects millions of individuals worldwide. Alcohol
consumption is a major contributor to the disease pathogenesis and ethanol-induced ulcer …

Attenuation of gastric mucosal damage by artesunate in rat: modulation of oxidative stress and NFκB mediated signaling

S Verma, VL Kumar - Chemico-biological interactions, 2016 - Elsevier
A number of factors like alcohol consumption, stress, use of non steroidal anti-inflammatory
drugs and acidity are well known to increase the risk of development of gastric ulcers. The …

Chemical characterization, toxicology and mechanism of gastric antiulcer action of essential oil from Gallesia integrifolia (Spreng.) Harms in the in vitro and in vivo …

K Arunachalam, SO Balogun, E Pavan… - Biomedicine & …, 2017 - Elsevier
Gallesia integrifolia is a Brazilian Amazon tree whose bark decoction is popularly used to
treat peptic ulcer. The essential oil from the inner stem bark of G. integrifolia (EOGi) was …

The ameliorative impacts of wheat germ oil against ethanol-induced gastric ulcers: Involvement of anti-inflammatory, antiapoptotic, and antioxidant activities

RS El-Shafey, SH Baloza, LA Mohammed… - Toxicology …, 2022 - academic.oup.com
This study examined if wheat germ oil (WGO) has gastroprotective impacts against ethanol-
induced gastric ulcer in rats. Rats were assigned into control, WGO, ethanol, omeprazole+ …

Evaluation of In Vivo Antiulcer Activity of Hydro‐Methanol Extract and Solvent Fractions of the Stem Bark of Ficus thonningii (Moraceae) on Rodent Models

H Adane, SA Atnafie, ZD Kifle… - BioMed Research …, 2021 - Wiley Online Library
Introduction. The stem bark of Ficus thonningii is used by Ethiopian traditional healers and
the community for the treatment of peptic ulcer disease. Thus, the current study was aimed at …

Sphaeranthus senegalensis DC: Evaluation of chemical constituents, oral safety, gastroprotective activity, and mechanism of action of its hydroethanolic extract

IY Sudi, MU Ahmed, B Adzu - Journal of ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Sphaeranthus senegalensis DC is a seasonal herb with a
spicy smell that grows wild in wet grounds of tropical Africa and Asia. The plant is used in …