Psychotic experiences in the general population, a review; definition, risk factors, outcomes and interventions
Psychotic experiences (PE) are common in the general population, in particular in
childhood, adolescence and young adulthood. PE have been shown to be associated with …
childhood, adolescence and young adulthood. PE have been shown to be associated with …
Meta-analytic prevalence of comorbid mental disorders in individuals at clinical high risk of psychosis: the case for transdiagnostic assessment
Comorbid mental disorders in subjects at clinical high risk for psychosis (CHR-P) may
impact preventive care. We conducted a PRISMA/MOOSE-compliant systematic meta …
impact preventive care. We conducted a PRISMA/MOOSE-compliant systematic meta …
Preventive psychiatry: a blueprint for improving the mental health of young people
Preventive approaches have latterly gained traction for improving mental health in young
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …
people. In this paper, we first appraise the conceptual foundations of preventive psychiatry …
Early intervention service systems for youth mental health: integrating pluripotentiality, clinical staging, and transdiagnostic lessons from early psychosis
Challenges associated with operationalising services for the at-risk mental state for
psychosis solely in that same diagnostic silo are increasingly well recognised—namely, the …
psychosis solely in that same diagnostic silo are increasingly well recognised—namely, the …
Polygenic risk scores for predicting outcomes and treatment response in psychiatry: hope or hype?
Over the last years, the decreased costs and enhanced accessibility to large genome-wide
association studies datasets have laid the foundations for the development of polygenic risk …
association studies datasets have laid the foundations for the development of polygenic risk …
Potential for prediction of psychosis and bipolar disorder in Child and Adolescent Mental Health Services: a longitudinal register study of all people born in Finland in …
Current strategies to predict psychosis identify only a small proportion of individuals at risk.
Additional strategies are needed to increase capacity for prediction and prevention of …
Additional strategies are needed to increase capacity for prediction and prevention of …
Diagnosis, prognosis, and treatment of brief psychotic episodes: a review and research agenda
Brief psychotic episodes represent an intriguing paradox in clinical psychiatry because they
elude the standard knowledge that applies to the persisting psychotic disorders such as …
elude the standard knowledge that applies to the persisting psychotic disorders such as …
Public health primary prevention implemented by clinical high-risk services for psychosis
A Estrade, G Salazar de Pablo, A Zanotti… - Translational …, 2022 - nature.com
Abstract Clinical High Risk for Psychosis (CHR-P) services have been primarily developed
to support young people with attenuated symptoms (indicated prevention). No evidence …
to support young people with attenuated symptoms (indicated prevention). No evidence …
Schizophrenia and the environment: within-person analyses may be required to yield evidence of unconfounded and causal association—the example of cannabis …
Hypotheses about the link between cannabis use and psychosis apply to the within-person
level but have been tested mostly at the between-person level. We used a within-person …
level but have been tested mostly at the between-person level. We used a within-person …
Examining the independent and joint effects of genomic and exposomic liabilities for schizophrenia across the psychosis spectrum
AimsPsychosis spectrum disorder has a complex pathoetiology characterised by interacting
environmental and genetic vulnerabilities. The present study aims to investigate the role of …
environmental and genetic vulnerabilities. The present study aims to investigate the role of …