Cell death pathways and viruses: role of microRNAs

JS Nahand, L Shojaie, SA Akhlagh… - … Therapy-Nucleic Acids, 2021 - cell.com
Viral infections lead to the death of more than a million people each year around the world,
both directly and indirectly. Viruses interfere with many cell functions, particularly critical …

Current state and challenges in developing respiratory syncytial virus vaccines

C Biagi, A Dondi, S Scarpini, A Rocca, S Vandini… - Vaccines, 2020 - mdpi.com
Respiratory syncytial virus (RSV) is the main cause of acute respiratory tract infections in
infants and it also induces significant disease in the elderly. The clinical course may be …

Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses

K Sedeyn, B Schepens, X Saelens - PLoS pathogens, 2019 - journals.plos.org
Human respiratory syncytial virus (RSV) is the most important cause of acute lower
respiratory tract disease in infants worldwide. As a first line of defense against respiratory …

[PDF][PDF] MicroRNAs in asthma and respiratory infections: identifying common pathways

S Taka, P Tzani-Tzanopoulou… - Allergy, asthma & …, 2019 - synapse.koreamed.org
MicroRNAs (miRs) are single-stranded RNAs of 18-25 nucleotides. These molecules
regulate gene expression at the post-transcriptional level; several of these are differentially …

Broad-spectrum inhibition of respiratory virus infection by microRNA mimics targeting p38 MAPK signaling

JL McCaskill, S Ressel, A Alber, J Redford… - … Therapy-Nucleic Acids, 2017 - cell.com
The majority of antiviral therapeutics target conserved viral proteins, however, this approach
confers selective pressure on the virus and increases the probability of antiviral drug …

Non-coding RNAs and their role in respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) infections

W Wu, EJ Choi, I Lee, YS Lee, X Bao - Viruses, 2020 - mdpi.com
Recent high-throughput sequencing revealed that only 2% of the transcribed human
genome codes for proteins, while the majority of transcriptional products are non-coding …

Autophagy, TGF-β, and SMAD-2/3 signaling regulates interferon-β response in respiratory syncytial virus infected macrophages

SM Pokharel, NK Shil, S Bose - Frontiers in cellular and infection …, 2016 - frontiersin.org
Human respiratory syncytial virus (RSV) is a lung tropic virus causing severe airway
diseases including bronchiolitis and pneumonia among infants, children, and immuno …

The importance of AGO 1 and 4 in post-transcriptional gene regulatory function of tRF5-GluCTC, an respiratory syncytial virus-induced tRNA-derived RNA fragment

EJ Choi, J Ren, K Zhang, W Wu, YS Lee, I Lee… - International journal of …, 2020 - mdpi.com
Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract
infection in infants, the elderly, and immune-compromised patients. It is also a significant …

[HTML][HTML] Versatile role of miR-24/24-1*/24-2* expression in cancer and other human diseases

S Mukherjee, B Shelar, S Krishna - American Journal of …, 2022 - ncbi.nlm.nih.gov
MiRNAs (miRs) have been proven to be well-validated therapeutic targets. Emerging
evidence has demonstrated that intricate, intrinsic and paradoxical functions of miRs are …

Regulatory role of MicroRNAs in muscle atrophy during exercise intervention

S Zhang, N Chen - International journal of molecular sciences, 2018 - mdpi.com
Skeletal muscle comprising approximately 40% of body weight is highly important for
locomotion and metabolic homeostasis. The growth and regeneration of skeletal muscle are …