Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …

The P450 family (CYP genes) of arthropods encodes diverse enzymes involved in the
metabolism of foreign compounds and in essential endocrine or ecophysiological functions …

Enzyme catalysis is gaining increasing importance in synthetic chemistry. Nowadays, the
growing number of biocatalysts accessible by means of bioinformatics and enzyme …

Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

Natural products, a chemically and structurally diverse class of molecules, possess a wide
spectrum of biological activities, have been used therapeutically for millennia, and have …

Conspectus Cytochrome P450 monooxygenase is a versatile oxidizing enzyme with great
potential in synthetic chemistry and biology. However, the dependence of its catalytic …

We report our investigation of the utility of peptide crosslinking cytochrome P450 enzymes
from biarylitide biosynthesis to generate a range of cyclic tripeptides from simple synthons …

Plants produce more than 20,000 nitrogen-containing heterocyclic metabolites called
alkaloids. These chemicals serve numerous eco-physiological functions in the plants as well …

The growing preference for producing cytochrome P450-mediated natural products in
microbial systems stems from the challenging nature of the organic chemistry approaches …