Tumoricidal photodynamic (PDT) and photothermal (PTT) therapies harness light to
eliminate cancer cells with spatiotemporal precision by either generating reactive oxygen …

Nanomedicine has emerged as a promising therapeutic approach, but its translation to the
clinic has been hindered by the lack of cellular models to anticipate how tumor cells will …

Pancreatic ductal adenocarcinoma (PDAC) is notorious for its resistance against
chemotherapy and immunotherapy due to its dense desmoplastic and immunosuppressive …

Monolayer cultures, the less standard three-dimensional (3D) culturing systems, and
xenografts are the main tools used in current basic and drug development studies of cancer …

The potential of photoactivating certain molecules, photosensitizers (PS), resulting in
photochemical processes, has long been realized in the form of photodynamic therapy …

The persistent failure of standard chemotherapy underscores the urgent need for innovative
and targeted approaches in cancer treatment. Photodynamic therapy (PDT) has emerged as …

Cetuximab (Cet)-IRDye800CW, among other antibody-IRDye800CW conjugates, is a
potentially effective tool for delineating tumor margins during fluorescence image-guided …

Photodynamic therapy (PDT) is a photochemistry-based treatment approach that relies on
the activation of photosensitizers by light to locally generate reactive oxygen species that …

The prognosis for patients with advanced-stage pancreatic ductal adenocarcinoma (PDAC)
remains dismal. It is generally accepted that combination cancer therapies offer the most …

Photoimmunotherapy (PIT) involves the targeted delivery of a photosensitizer through
antibody conjugation, which, upon binding to its cellular target and activation by external …