Abstract Growth differentiation factor 15 (GDF15) is a member of the TGFβ superfamily
whose expression is increased in response to cellular stress and disease as well as by …

Introduction: Cytokines are a diverse group of peptides produced by different cell types
including cancer cells and various subpopulations of immune system cells. They exert their …

GDF15 has recently gained scientific and translational prominence with the discovery that its
receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain …

In search of metabolically regulated secreted proteins, we conducted a microarray study
comparing gene expression in major metabolic tissues of fed and fasted ob/ob mice and …

Growth differentiation factor 15 or macrophage inhibitory cytokine-1 (GDF15/MIC-1) is a
divergent member of the transforming growth factor β superfamily and has a diverse …

Abstract Growth differentiation factor 15 (GDF15) is a peptide hormone, and a divergent
member of the transforming growth factor beta (TGFβ) superfamily. In normal physiology …

Using molecular, cellular, and genetic approaches, recent studies examining the role of the
bone morphogenetic protein (BMP) family of growth factors in the reproductive system have …

MEG3 is a maternally expressed imprinted gene suggested to function as a non-coding
RNA. Our previous studies suggest that MEG3 has a function of tumor suppression. The …

Abstract GDF-15 (also MIC-1, NAG-1, PLAB, PTGFB) is a member of the TGF-β superfamily,
which is widely distributed in mammalian tissues and has been shown to play multiple roles …

A ketogenic diet (KD) has been promoted as an obesity management diet, yet its underlying
mechanism remains elusive. Here we show that KD reduces energy intake and body weight …