Traumatic brain injury (TBI) is a chronic and progressive disease, and management requires
an understanding of both the primary neurological injury and the secondary sequelae that …

In pulmonary arterial hypertension (PAH), right ventricular (RV) adaptation is essential to
overcome the chronic increases in RV pressure overload. Ultimately, RV compensatory …

Despite advances in the treatment of heart failure, prognosis is poor, mortality high and there
remains no cure. Heart failure is associated with reduced cardiac pump function, autonomic …

Background: The beneficial effects of parasympathetic stimulation have been reported in left
heart failure, but whether it would be beneficial for pulmonary arterial hypertension (PAH) …

Abstract Background Trastuzumab (Trz)-induced cardiotoxicity (TIC) is one of the most
common adverse effects of targeted anticancer agents. Although oxidative stress …

Cardiovascular disease remains a major cause of disability and death worldwide.
Autonomic imbalance, characterized by suppressed vagal (parasympathetic) activity and …

The autonomic influences on the heart have a ying-yang nature, albeit oversimplified, the
interplay between the sympathetic and parasympathetic system (known as the cholinergic …

The autonomic nervous system is an important modulator of cardiac signaling in both health
and disease. In fact, the significance of altered parasympathetic tone in cardiac disease has …

We previously reported that cholinergic stimulation with pyridostigmine (PY) induces anti-
inflammatory cell recruitment soon after myocardial infarction (MI). In this study, we …

Spectral analysis of heart rate (HR) has been widely used to assess the autonomic
cardiovascular control. A nonlinear approach, known as symbolic analysis, has been …