Genetics of complex traits: prediction of phenotype, identification of causal polymorphisms and genetic architecture

ME Goddard, KE Kemper… - … of the Royal …, 2016 - royalsocietypublishing.org
Complex or quantitative traits are important in medicine, agriculture and evolution, yet, until
recently, few of the polymorphisms that cause variation in these traits were known. Genome …

An equation to predict the accuracy of genomic values by combining data from multiple traits, populations, or environments

YCJ Wientjes, P Bijma, RF Veerkamp, MPL Calus - Genetics, 2016 - academic.oup.com
Predicting the accuracy of estimated genomic values using genome-wide marker
information is an important step in designing training populations. Currently, different …

Genomic correlation: harnessing the benefit of combining two unrelated populations for genomic selection

LR Porto-Neto, W Barendse, JM Henshall… - Genetics Selection …, 2015 - Springer
Background The success of genomic selection in animal breeding hinges on the availability
of a large reference population on which genomic-based predictions of additive genetic or …

A predictive assessment of genetic correlations between traits in chickens using markers

M Momen, AA Mehrgardi, A Sheikhy… - Genetics Selection …, 2017 - Springer
Background Genomic selection has been successfully implemented in plant and animal
breeding programs to shorten generation intervals and accelerate genetic progress per unit …

Genomic predictions in Korean Hanwoo cows: a comparative analysis of genomic BLUP and bayesian methods for Reproductive traits

MA Haque, YM Lee, JJ Ha, S Jin, B Park, NY Kim… - Animals, 2023 - mdpi.com
Simple Summary Historically, Korea has been an agrarian society where cattle played a
significant role in Korean culture as working animals. However, in recent decades, there has …

Rare variants in transcript and potential regulatory regions explain a small percentage of the missing heritability of complex traits in cattle

O Gonzalez-Recio, HD Daetwyler, IM MacLeod… - PloS one, 2015 - journals.plos.org
The proportion of genetic variation in complex traits explained by rare variants is a key
question for genomic prediction, and for identifying the basis of “missing heritability”–the …

A meta-analysis of the gap between pedigree-based and genomic heritability estimates for production traits in dairy cows

H Khanzadeh, NG Hossein-Zadeh, S Ghovvati - Livestock Science, 2022 - Elsevier
This study aimed to conduct a meta-analysis based on a random-effects model to combine
different published pedigree-based and genomic heritability estimates for production traits in …

Contribution of rare and low-frequency whole-genome sequence variants to complex traits variation in dairy cattle

Q Zhang, MPL Calus, B Guldbrandtsen… - Genetics Selection …, 2017 - Springer
Background Whole-genome sequencing and imputation methodologies have enabled the
study of the effects of genomic variants with low to very low minor allele frequency (MAF) on …

The Iterative Exclusion of Compatible Samples Workflow for Multi-SNP Analysis in Complex Diseases

W Xu, X Zhu, L Zhang, J Gao - Algorithms, 2023 - mdpi.com
Complex diseases are affected by various factors, and single-nucleotide polymorphisms
(SNPs) are the basis for their susceptibility by affecting protein structure and gene …

Compression distance can discriminate animals by genetic profile, build relationship matrices and estimate breeding values

NJ Hudson, L Porto-Neto, JW Kijas… - Genetics Selection …, 2015 - Springer
Background Genetic relatedness is currently estimated by a combination of traditional
pedigree-based approaches (ie numerator relationship matrices, NRM) and, given the …