Parahydrogen is demonstrated to efficiently transfer its nuclear spin hyperpolarization to
nitrogen-15 in pyridine and nicotinamide (vitamin B3 amide) by conducting “signal …

1H NMR signal amplification by reversible exchange (SABRE) was observed for pyridine
and pyridine-d 5 at 9.4 T, a field that is orders of magnitude higher than what is typically …

SABRE is a nuclear spin hyperpolarization technique based on the reversible association of
a substrate molecule and para-hydrogen (p-H2) to a metal complex. During the lifetime of …

[IrCl (COE) 2] 2 (1) reacts with pyridine (py) and H2 to form crystallographically characterized
IrCl (H) 2 (COE)(py) 2 (2). 2 undergoes py loss to form 16-electron IrCl (H) 2 (COE)(py)(3) …

N-Heterocycles are ubiquitous in biologically active natural products and pharmaceuticals.
Yet, new syntheses and modifications of N-heterocycles are continually of interest for the …

This thesis aims to elucidate mechanisms of palladium and iridium catalysis using para-H2.
In palladium catalysis, the debate on the nature of the active catalysts tends to focus on …