Veterinary medicine needs new green antimicrobial drugs
Given that:(1) the worldwide consumption of antimicrobial drugs (AMDs) used in food-
producing animals will increase over the coming decades;(2) the prudent use of AMDs will …
producing animals will increase over the coming decades;(2) the prudent use of AMDs will …
Intramuscular therapeutic doses of enrofloxacin affect microbial community structure but not the relative abundance of fluoroquinolones resistance genes in swine …
X Li, X Tang, M Chen, S Wang, C Tong, J Xu… - Science of The Total …, 2024 - Elsevier
Livestock manure is a major source of veterinary antibiotics and antibiotic resistance genes
(ARGs). Elucidation of the residual characteristics of ARGs in livestock manure following the …
(ARGs). Elucidation of the residual characteristics of ARGs in livestock manure following the …
Comparisons of plasma and fecal pharmacokinetics of danofloxacin and enrofloxacin in healthy and Mannheimia haemolytica infected calves
Danofloxacin and enrofloxacin are fluoroquinolones (FQs) used to treat and control bovine
respiratory disease (BRD) complex. While low toxicity, high bactericidal activity, and …
respiratory disease (BRD) complex. While low toxicity, high bactericidal activity, and …
Targeted dosing for susceptible heteroresistant subpopulations may improve rational dosage regimen prediction for colistin in broiler chickens
A Mead, PL Toutain, P Richez, L Pelligand - Scientific Reports, 2023 - nature.com
The dosage of colistin for the treatment of enteric E. coli in animals necessitates considering
the heteroresistant (HR) nature of the targeted inoculum, described by the presence of a …
the heteroresistant (HR) nature of the targeted inoculum, described by the presence of a …
Enrofloxacin alters fecal microbiota and resistome irrespective of its dose in calves
AF Beyi, D Brito-Goulart, T Hawbecker, B Ruddell… - Microorganisms, 2021 - mdpi.com
Enrofloxacin is a fluoroquinolone drug used to prevent and control bovine respiratory
disease (BRD) complex in multiple or single doses, ranging from 7.5 to 12.5 mg/kg body …
disease (BRD) complex in multiple or single doses, ranging from 7.5 to 12.5 mg/kg body …
Effects of danofloxacin dosing regimen on gastrointestinal pharmacokinetics and fecal microbiome in steers
Fluoroquinolones are a class of antimicrobial commonly used in human medicine, and
deemed critical by the World Health Organization. Nonetheless, two formulations are …
deemed critical by the World Health Organization. Nonetheless, two formulations are …
Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers
Antimicrobial drug concentrations in the gastrointestinal tract likely drive antimicrobial
resistance in enteric bacteria. Our objective was to determine the concentration of ceftiofur …
resistance in enteric bacteria. Our objective was to determine the concentration of ceftiofur …
Pharmacokinetics of Colistin in the Gastrointestinal Tract of Poultry Following Dosing via Drinking Water and Its Bactericidal Impact on Enteric Escherichia coli
A Mead, P Richez, S Azzariti… - Frontiers in Veterinary …, 2021 - frontiersin.org
Colistin, a last-line antibiotic of major importance in veterinary medicine and of critical
importance in human medicine, is authorized to treat gastrointestinal (enteric) infections …
importance in human medicine, is authorized to treat gastrointestinal (enteric) infections …
Dosing regimen of enrofloxacin impacts intestinal pharmacokinetics and the fecal microbiota in steers
KM Ferguson, ME Jacob, CM Theriot… - Frontiers in …, 2018 - frontiersin.org
Objective: The intestinal concentrations of antimicrobial drugs that select for resistance in
fecal bacteria of cattle are poorly understood. Our objective was to associate active drug …
fecal bacteria of cattle are poorly understood. Our objective was to associate active drug …
Quantifying trade-offs between therapeutic efficacy and resistance dissemination for enrofloxacin dose regimens in cattle
The use of antimicrobial drugs in food-producing animals contributes to the selection
pressure on pathogenic and commensal bacteria to become resistant. This study aims to …
pressure on pathogenic and commensal bacteria to become resistant. This study aims to …