The OmpA family of proteins: roles in bacterial pathogenesis and immunity

AW Confer, S Ayalew - Veterinary microbiology, 2013 - Elsevier
The OmpA family of outer membrane proteins is a group of genetically related, heat-
modifiable, surface-exposed, porin proteins that are in high-copy number in the outer …

[HTML][HTML] Seventy years of Chlamydia vaccine research–limitations of the past and directions for the future

S Phillips, BL Quigley, P Timms - Frontiers in microbiology, 2019 - frontiersin.org
Chlamydia is a major bacterial pathogen that infects humans, as well as a wide range of
animals, including marsupials, birds, cats, pigs, cattle, and sheep. Antibiotics are the only …

Animal models for studying female genital tract infection with Chlamydia trachomatis

E De Clercq, I Kalmar, D Vanrompay - Infection and immunity, 2013 - Am Soc Microbiol
Chlamydia trachomatis is a Gram-negative obligate intracellular bacterial pathogen. It is the
leading cause of bacterial sexually transmitted disease in the world, with more than 100 …

Domestic animal models for biomedical research

A Bähr, E Wolf - Reproduction in domestic animals, 2012 - Wiley Online Library
Contents Experimental animals in biomedical research provide insights into disease
mechanisms and models for determining the efficacy and safety of new therapies and for …

The Duration of Chlamydia muridarum Genital Tract Infection and Associated Chronic Pathological Changes Are Reduced in IL-17 Knockout Mice but Protection Is …

DW Andrew, M Cochrane, JH Schripsema… - PloS one, 2013 - journals.plos.org
IL-17 is believed to be important for protection against extracellular pathogens, where
clearance is dependent on neutrophil recruitment and local activation of epithelial cell …

The mouse model of Chlamydia genital tract infection: a review of infection, disease, immunity and vaccine development

CP O'Meara, DW Andrew… - Current molecular …, 2014 - ingentaconnect.com
Chlamydia trachomatis is the most common sexually transmitted bacterial infection
worldwide. The impact of this pathogen on human reproduction has intensified research …

Immunity, immunopathology, and human vaccine development against sexually transmitted Chlamydia trachomatis

J Rey-Ladino, AGP Ross, AW Cripps - Human Vaccines & …, 2014 - Taylor & Francis
This review examines the immunity, immunopathology, and contemporary problems of
vaccine development against sexually transmitted Chlamydia trachomatis. Despite improved …

Evaluation of a multisubunit recombinant polymorphic membrane protein and major outer membrane protein T cell vaccine against Chlamydia muridarum genital …

H Yu, KP Karunakaran, X Jiang, RC Brunham - Vaccine, 2014 - Elsevier
An efficacious vaccine is needed to control Chlamydia trachomatis infection. In the murine
model of Chlamydia muridarum genital infection, multifunctional mucosal CD4 T cells are …

Development of a Chlamydia trachomatis vaccine for urogenital infections: novel tools and new strategies point to bright future prospects

LM Hafner, P Timms - Expert review of vaccines, 2018 - Taylor & Francis
Introduction: The “cloaked “bacterial pathogen that is Chlamydia trachomatis continues to
cause sexually transmitted infections (STIs) that adversely affect the health and well-being of …

[PDF][PDF] Recent advances in epidemiology, pathology and immunology of veterinary Chlamydiae

K Sachse, N Borel - Chlamydia Biology: From Genome to Disease, 2020 - researchgate.net
The veterinary chlamydiae comprise all currently known organisms of the family
Chlamydiaceae, except Chlamydia trachomatis. C. abortus is an economically important …