Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are secreted by most cells and contain various bioactive molecules reflecting their cellular origin …
JE Blume, WC Manning, G Troiano, D Hornburg… - Nature …, 2020 - nature.com
Large-scale, unbiased proteomics studies are constrained by the complexity of the plasma proteome. Here we report a highly parallel protein quantitation platform integrating …
VP Chavda, AB Patel, KJ Mistry, SF Suthar… - Frontiers in …, 2022 - frontiersin.org
Cancer is a prominent cause of mortality globally, and it becomes fatal and incurable if it is delayed in diagnosis. Chemotherapy is a type of treatment that is used to eliminate …
TM Abu Samaan, M Samec, A Liskova, P Kubatka… - Biomolecules, 2019 - mdpi.com
Paclitaxel (PTX), the most widely used anticancer drug, is applied for the treatment of various types of malignant diseases. Mechanisms of PTX action represent several ways in …
Combination chemotherapy is widely exploited for enhanced cancer treatment in the clinic. However, the traditional cocktail administration of combination regimens often suffers from …
G Ioele, M Chieffallo, MA Occhiuzzi, M De Luca… - Molecules, 2022 - mdpi.com
In past decades, anticancer research has led to remarkable results despite many of the approved drugs still being characterized by high systemic toxicity mainly due to the lack of …
E Bernabeu, M Cagel, E Lagomarsino… - International journal of …, 2017 - Elsevier
In recent years, the nanotechnology has offered researchers the opportunity to solve the problems caused by the vehicle of the standard and first formulation of paclitaxel (Taxol®) …
Simple Summary Microtubules (MTs) are highly conserved proteins present in all eukaryotic organisms. They form the cell cytoskeleton, and its function is essential for a large number of …
L Yan, J Shen, J Wang, X Yang, S Dong… - Dose …, 2020 - journals.sagepub.com
Chemotherapy is widely used to treat cancer. The toxic effect of conventional chemotherapeutic drugs on healthy cells leads to serious toxic and side effects of …