Accumulating evidence shows that cellular and acellular components in tumor
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …

Malignant cells support tumor proliferation and progression by adopting to metabolic
changes. Tumor cells altered metabolism by increasing glucose uptake and fermentation of …

A number of studies have shown that aspirin, as commonly prescribed drug, prevents the
development of hepatocellular carcinoma (HCC). Ferroptosis as a dynamic tumor …

In cancerous cells, significant changes occur in the activity of signaling pathways affecting a
wide range of cellular activities ranging from growth and proliferation to apoptosis …

Hepatocellular carcinoma (HCC) is a primary liver cancer that usually develops in the setting
of chronic inflammation and liver damage. The hepatic microenvironment plays a crucial role …

Cancer cells often encounter hypoxic and hypo-nutrient conditions, which force them to
make adaptive changes to meet their high demands for energy and various biomaterials for …

Non-small-cell lung cancer (NSCLC) is one of the deadliest cancers in the world. Circular
RNA (circRNA) has been shown to participate in oncogenesis regulation, including lung …

Abnormal lipid metabolism plays crucial roles in the development of cancer. Spindlin 1
(SPIN1) involving the process of spindle organization and chromosomal stability serves as …

Background Our prior studies have shown that inflammation may play an important
triggering role during the process of denervated muscle atrophy. The nonsteroidal anti …

Glucose metabolism reprogramming is one of the hallmarks of cancer cells, although
functional and regulatory mechanisms of long noncoding RNA (lncRNA) in the contribution …