Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …

The influenza virus is a global threat to human health causing unpredictable yet recurring
pandemics, the last four emerging over the course of a hundred years. As our knowledge of …

Abstract Clade 2.3. 4.4 b H5N1 is causing an unprecedented outbreak in dairy cows in the
United States. To understand if recent H5N1 viruses are changing their receptor use, we …

Mucin type O‐glycosylation is one of the most diverse types of glycosylation, playing
essential roles in tissue development and homeostasis. In complex organisms, O‐GalNAc …

Acute respiratory distress syndrome (ARDS) is a fatal complication of influenza infection. In
this Review we provide an integrated model for its pathogenesis. ARDS involves damage to …

The 2018–2019 period marks the centennial of the “Spanish” influenza pandemic, which
caused at least 50 million deaths worldwide. The unprecedented nature of the pandemic's …

Viral infections are initiated by attachment of the virus to host cell surface receptors,
including sialic acid-containing glycans. It is now possible to rapidly identify specific glycan …

The effectiveness of the annual influenza vaccine has declined in recent years, especially
for the H3N2 component, and is a concern for global public health. A major cause for this …

The recent emergence of a novel avian A/H 7 N 9 influenza virus in poultry and humans in C
hina, as well as laboratory studies on adaptation and transmission of avian A/H 5 N 1 …

Newly emerging or" re-emerging" viral diseases continue to pose significant global public
health threats. Prototypic are influenza viruses that are major causes of human respiratory …