Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trials

L Wang, PJ Hong, C May, Y Rehman, Y Oparin… - Bmj, 2021 - bmj.com
Objective To determine the benefits and harms of medical cannabis and cannabinoids for
chronic pain. Design Systematic review and meta-analysis. Data sources MEDLINE …

The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations

S Petrosino, V Di Marzo - British journal of pharmacology, 2017 - Wiley Online Library
Palmitoylethanolamide (PEA) has emerged as a potential nutraceutical, because this
compound is naturally produced in many plant and animal food sources, as well as in cells …

Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline

JW Busse, P Vankrunkelsven, L Zeng, AF Heen… - bmj, 2021 - bmj.com
Clinical question What is the role of medical cannabis or cannabinoids for people living with
chronic pain due to cancer or non-cancer causes? Current practice Chronic pain is common …

Systematic review of endometriosis pain assessment: how to choose a scale?

N Bourdel, J Alves, G Pickering, I Ramilo… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Numerous studies concerning endometriosis and pain have been reported.
However, there is no consensus on the best method to evaluate pain in endometriosis and …

Palmitoylethanolamide: a natural compound for health management

P Clayton, M Hill, N Bogoda, S Subah… - International journal of …, 2021 - mdpi.com
All nations which have undergone a nutrition transition have experienced increased
frequency and falling latency of chronic degenerative diseases, which are largely driven by …

Mast cell-mediated mechanisms of nociception

A Aich, LB Afrin, K Gupta - International journal of molecular sciences, 2015 - mdpi.com
Mast cells are tissue-resident immune cells that release immuno-modulators, chemo-
attractants, vasoactive compounds, neuropeptides and growth factors in response to …

Palmitoylethanolamide for the treatment of pain: pharmacokinetics, safety and efficacy

L Gabrielsson, S Mattsson… - British journal of clinical …, 2016 - Wiley Online Library
Palmitoylethanolamide (PEA) has been suggested to have useful analgesic properties and
to be devoid of unwanted effects. Here, we have examined critically this contention, and …

Palmitoylethanolamide in the treatment of chronic pain: a systematic review and meta-analysis of double-blind randomized controlled trials

K Lang-Illievich, C Klivinyi, C Lasser, CTA Brenna… - Nutrients, 2023 - mdpi.com
Chronic pain is a major source of morbidity for which there are limited effective treatments.
Palmitoylethanolamide (PEA), a naturally occurring fatty acid amide, has demonstrated utility …

The effects of nutrients on symptoms in women with endometriosis: a systematic review

E Huijs, A Nap - Reproductive BioMedicine Online, 2020 - Elsevier
The success rate of medical and surgical treatment for endometriosis is limited. Empowering
patients suffering from endometriosis by giving them opportunities to positively influence …

Variation in outcome reporting in endometriosis trials: a systematic review

M Hirsch, JMN Duffy, JO Kusznir, CJ Davis… - American journal of …, 2016 - Elsevier
Objective We reviewed the outcomes and outcome measures reported in randomized
controlled trials and their relationship with methodological quality, year of publication …