Recent evidence of non-rapid eye movement sleep oscillation abnormalities in psychiatric disorders

A Mayeli, C Sanguineti, F Ferrarelli - Current Psychiatry Reports, 2024 - Springer
Abstract Purpose of Review We review recent studies published from 2019 to 2024
examining slow waves and sleep spindles abnormalities across neurodevelopmental …

Potential diagnostic biomarkers for schizophrenia

W Yue, H Huang, J Duan - Medical Review, 2022 - degruyter.com
Schizophrenia (SCH) is a complex and severe mental disorder with high prevalence,
disability, mortality and carries a heavy disease burden, the lifetime prevalence of SCH is …

A potential source of bias in group-level EEG microstate analysis

M Murphy, J Wang, C Jiang, LA Wang, N Kozhemiako… - Brain Topography, 2024 - Springer
Microstate analysis is a promising technique for analyzing high-density
electroencephalographic data, but there are multiple questions about methodological best …

Sleep spindle alterations relate to working memory deficits in individuals at clinical high-risk for psychosis

A Mayeli, JD Wilson, FL Donati, AD LaGoy, F Ferrarelli - Sleep, 2022 - academic.oup.com
Abstract Study Objectives Sleep spindles are waxing and waning EEG waves exemplifying
the main fast oscillatory activity occurring during NREM sleep. Several recent studies have …

Mouse mutants in schizophrenia risk genes GRIN2A and AKAP11 show EEG abnormalities in common with schizophrenia patients

LE Herzog, L Wang, E Yu, S Choi, Z Farsi… - Translational …, 2023 - nature.com
Schizophrenia is a heterogeneous psychiatric disorder with a strong genetic basis, whose
etiology and pathophysiology remain poorly understood. Exome sequencing studies have …

Transient oscillation dynamics during sleep provide a robust basis for electroencephalographic phenotyping and biomarker identification

PA Stokes, P Rath, T Possidente, M He, S Purcell… - Sleep, 2023 - academic.oup.com
Transient oscillatory events in the sleep electroencephalogram represent short-term
coordinated network activity. Of particular importance, sleep spindles are transient …

A spectrum of altered non-rapid eye movement sleep in schizophrenia

N Kozhemiako, C Jiang, Y Sun, Z Guo, S Chapman… - Sleep, 2024 - academic.oup.com
Multiple facets of sleep neurophysiology, including electroencephalography (EEG) metrics
such as non-rapid eye movement (NREM) spindles and slow oscillations, are altered in …

Study Protocol: Global Research Initiative on the Neurophysiology of Schizophrenia (GRINS) project

J Wang, C Jiang, Z Guo, S Chapman, N Kozhemiako… - BMC psychiatry, 2024 - Springer
Background Objective and quantifiable markers are crucial for developing novel
therapeutics for mental disorders by 1) stratifying clinically similar patients with different …

Spindle chirp and other sleep oscillatory features in young children with autism

D Cumming, N Kozhemiako, AE Thurm, CA Farmer… - Sleep Medicine, 2024 - Elsevier
Objectives To determine whether spindle chirp and other sleep oscillatory features differ in
young children with and without autism. Methods Automated processing software was used …

Reduced slow wave density is associated with worse positive symptoms in clinical high risk: An objective readout of symptom severity for early treatment interventions …

A Mayeli, JD Wilson, FL Donati, F Ferrarelli - Psychiatry Research, 2024 - Elsevier
Individuals at clinical high risk for psychosis (CHR) present subsyndromal psychotic
symptoms that can escalate and lead to the transition to a diagnosable psychotic disorder …