Particulate matter toxicity is Nrf2 and mitochondria dependent: the roles of metals and polycyclic aromatic hydrocarbons

M Pardo, X Qiu, R Zimmermann… - Chemical research in …, 2020 - ACS Publications
Particulate matter (PM), an important component of air pollution, induces significant adverse
health effects. Many of the observed health effects caused by inhaled PM are associated …

Effect of atmospheric aging on soot particle toxicity in lung cell models at the air–liquid interface: differential toxicological impacts of biogenic and anthropogenic …

S Offer, E Hartner, S Di Bucchianico… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Secondary organic aerosols (SOAs) formed from anthropogenic or biogenic
gaseous precursors in the atmosphere substantially contribute to the ambient fine particulate …

Pathogenic mechanisms of secondary organic aerosols

T Déméautis, M Delles, S Tomaz… - Chemical Research …, 2022 - ACS Publications
Air pollution represents a major health problem and an economic burden. In recent years,
advances in air pollution research has allowed particle fractionation and identification of …

Oxidized and unsaturated: Key organic aerosol traits associated with cellular reactive oxygen species production in the southeastern United States

F Liu, T Joo, JC Ditto, MG Saavedra… - Environmental …, 2023 - ACS Publications
Exposure to ambient fine particulate matter (PM2. 5) is associated with millions of premature
deaths annually. Oxidative stress through overproduction of reactive oxygen species (ROS) …

[HTML][HTML] Exposure to naphthalene and β-pinene-derived secondary organic aerosol induced divergent changes in transcript levels of BEAS-2B cells

M Pardo, S Offer, E Hartner, S Di Bucchianico… - Environment …, 2022 - Elsevier
The health effects of exposure to secondary organic aerosols (SOAs) are still limited. Here,
we investigated and compared the toxicities of soot particles (SP) coated with β-pinene SOA …

Simultaneous optical photothermal infrared (O-PTIR) and Raman spectroscopy of submicrometer atmospheric particles

NE Olson, Y Xiao, Z Lei, AP Ault - Analytical Chemistry, 2020 - ACS Publications
Physicochemical analysis of individual atmospheric aerosols at the most abundant sizes in
the atmosphere (< 1 μm) is analytically challenging, as hundreds to thousands of species …

Variations and sources of organic aerosol in winter Beijing under markedly reduced anthropogenic activities during COVID-2019

R Hu, S Wang, H Zheng, B Zhao, C Liang… - … science & technology, 2021 - ACS Publications
The COVID-19 outbreak provides a “controlled experiment” to investigate the response of
aerosol pollution to the reduction of anthropogenic activities. Here we explore the chemical …

Toxicity of water-and organic-soluble wood tar fractions from biomass burning in lung epithelial cells

M Pardo, C Li, Z Fang, S Levin-Zaidman… - Chemical research in …, 2021 - ACS Publications
Widespread smoke from wildfires and biomass burning contributes to air pollution and the
deterioration of air quality and human health. A common and major emission of biomass …

Heterogeneous Oxidation Products of Fine Particulate Isoprene Epoxydiol-Derived Methyltetrol Sulfates Increase Oxidative Stress and Inflammatory Gene Responses …

F Khan, Y Chen, HJ Hartwell, J Yan… - Chemical Research …, 2023 - ACS Publications
Hydroxyl radical (· OH)-initiated oxidation of isoprene, the most abundant nonmethane
hydrocarbon in the atmosphere, is responsible for substantial amounts of secondary organic …

Kinetics and Products of Heterogeneous Hydroxyl Radical Oxidation of Isoprene Epoxydiol-Derived Secondary Organic Aerosol

J Yan, Y Zhang, Y Chen, NC Armstrong… - ACS Earth and Space …, 2023 - ACS Publications
Heterogeneous hydroxyl radical (• OH) oxidation is an important aging process for isoprene
epoxydiol-derived secondary organic aerosol (IEPOX-SOA) that alters its chemical …