Our ancestral diet consisted of much more nondigestible fiber than that of many societies
today. Thus, from an evolutionary perspective the human genome and its physiological and …

Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

Changes in gut microbiota have been associated with several diseases. Here, the
International Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of …

The gut microbiota (GM) is defined as the community of microorganisms (bacteria, archaea,
fungi, viruses) colonizing the gastrointestinal tract. GM regulates various metabolic pathways …

Probiotics can effectively improve ulcerative colitis (UC), but the mechanism is still unclear.
Here, shotgun metagenome and transcriptome analyses were performed to explore the …

Inulin consumption in both humans and animal models is recognized for its prebiotic action
with the most consistent change that lies in enhancing the growth and functionality of …

Considerable evidence points to the critical role of the gut microbiota in physiology and
disease. The administration of live microbes as a therapeutic modality is increasingly being …

Short-chain fatty acids (SCFAs) are the main metabolites produced by the bacterial
fermentation of dietary fiber, and they play a critical role in the maintenance of intestinal …

Berberine (BBR), an isoquinoline alkaloid, has been found in many plants, such as Coptis
chinensis Franch and Phellodendron chinense Schneid. Although BBR has a wide spectrum …

Emerging evidence indicates that gut microbiota affect the response to anticancer therapies
by modulating the host immune system. In this study, we investigated the impact of gut …