Dmrt genes in the development and evolution of sexual dimorphism

A Kopp - Trends in Genetics, 2012 - cell.com
Most animals are sexually dimorphic, but different taxa have different sex-specific traits.
Despite major differences in the genetic control of sexual development among animal …

Vive la difference: males vs females in flies vs worms

TW Cline, BJ Meyer - Annual review of genetics, 1996 - annualreviews.org
▪ Abstract For 600 million years, the two best-understood metazoan species, the nematode
Caenorhabditis elegans and the fruit fly Drosophila melanogaster, have developed …

Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle

K Horiuchi, T Kawamura, H Iwanari, R Ohashi… - Journal of Biological …, 2013 - ASBMB
Wilms' tumor 1-associating protein (WTAP) is a putative splicing regulator that is thought to
be required for cell cycle progression through the stabilization of cyclin A2 mRNA and …

Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides

KC Burtis, BS Baker - Cell, 1989 - cell.com
The doublesex (dsx) gene regulates somatic sexual differentiation in both sexes in D.
melanogaster. Two functional products are encoded by dsx: one product is expressed in …

Transforming insect population control with precision guided sterile males with demonstration in flies

NP Kandul, J Liu, HM Sanchez C, SL Wu… - Nature …, 2019 - nature.com
The sterile insect technique (SIT) is an environmentally safe and proven technology to
suppress wild populations. To further advance its utility, a novel CRISPR-based technology …

Nova regulates brain-specific splicing to shape the synapse

J Ule, A Ule, J Spencer, A Williams, JS Hu, M Cline… - Nature …, 2005 - nature.com
Alternative RNA splicing greatly increases proteome diversity and may thereby contribute to
tissue-specific functions. We carried out genome-wide quantitative analysis of alternative …

[PDF][PDF] Eukaryotic transcriptional regulatory proteins

PF Johnson, SL McKnight - Annual review of biochemistry, 1989 - researchgate.net
The past five years have offered a virtual explosion of information in the field of eukaryotic
gene regulation. The natural anticipation that a considerable degree of regulation would be …

[PDF][PDF] RNA-binding proteins as developmental regulators

RJ Bandziulis, MS Swanson, G Dreyfuss - Genes Dev, 1989 - academia.edu
Many RNA-binding proteins of the nucleus and cytoplasm, including pre-mRNA-, mRNA-,
snRNA-, and pre-rRNA-binding proteins, contain a putative RNA-binding domain of …

HIV-1 structural gene expression requires binding of the Rev trans-activator to its RNA target sequence

MH Malim, LS Tiley, DF McCarn, JR Rusche, J Hauber… - Cell, 1990 - cell.com
Expression of human immunodeficiency virus type 1 structural proteins requires both the
viral Rev fransactivator and its &-acting RNA target sequence, the Rev response element …

Control of doublesex Alternative Splicing by transformer and transformer-2 in Drosophila

K Hoshijima, K Inoue, I Higuchi, H Sakamoto… - Science, 1991 - science.org
Sex-specific alternative processing of doublesex (dsx) precursor messenger RNA (pre-
mRNA) regulates somatic sexual differentiation in Drosophila melanogaster. Cotransfection …