Consensus guidelines for therapeutic drug monitoring in neuropsychopharmacology: update 2017

C Hiemke, N Bergemann, HW Clement… - …, 2018 - thieme-connect.com
Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …

Postpartum depression: pathophysiology, treatment, and emerging therapeutics

DE Stewart, SN Vigod - Annual review of medicine, 2019 - annualreviews.org
Postpartum depression (PPD) is common, disabling, and treatable. The strongest risk factor
is a history of mood or anxiety disorder, especially having active symptoms during …

Postpartum depression

DE Stewart, S Vigod - New England Journal of Medicine, 2016 - Mass Medical Soc
Key Clinical Points Postpartum Depression Postpartum depression is a common, disabling,
and treatable problem that affects the woman, infant, and family. Sensitive inquiry about …

Sex differences in the psychopharmacological treatment of depression

JJ Sramek, MF Murphy, NR Cutler - Dialogues in clinical …, 2016 - Taylor & Francis
Although a number of studies have observed that females respond better to serotonergic
antidepressants than males and that postmenopausal females have a diminished response …

The anti-inflammatory mechanism of antidepressants–SSRIs, SNRIs

P Gałecki, J Mossakowska-Wójcik… - Progress in Neuro …, 2018 - Elsevier
The cytokine theory of depression no longer brings about any doubts. Experiments and
research studies conducted in the last ten years have confirmed that both physical and …

Venlafaxine's therapeutic reference range in the treatment of depression revised: a systematic review and meta-analysis

XM Lense, C Hiemke, CSM Funk… - …, 2024 - Springer
Introduction The selective serotonin and norepinephrine reuptake inhibitor venlafaxine is
among the most prescribed antidepressant drugs worldwide and, according to guidelines, its …

Therapeutic drug monitoring of venlafaxine in an everyday clinical setting: analysis of age, sex and dose concentration relationships

MR Hansen, IB Kuhlmann, A Pottegård… - Basic & Clinical …, 2017 - Wiley Online Library
Venlafaxine is a commonly used antidepressant agent. We aimed to provide detailed
information on the associations between venlafaxine dose and concentrations of …

Analysis of smoking behavior on the pharmacokinetics of antidepressants and antipsychotics: evidence for the role of alternative pathways apart from CYP1A2

M Scherf-Clavel, L Samanski… - International clinical …, 2019 - journals.lww.com
Smoking is common among psychiatric patients and has been shown to accelerate the
metabolism of different drugs. We aimed to determine the effect of smoking on the serum …

Pharmacodynamic Drug–Drug interactions of QT-prolonging drugs in hospitalized psychiatric patients

G Hefner, M Hahn, C Hiemke, S Toto, J Wolff… - Journal of Neural …, 2021 - Springer
At least 170 approved drugs are linked to QT prolongation, which can lead to serious
adverse drug reactions (ADRs), such as Torsade de Pointes (TdP). The aim of this study was …

Higher venlafaxine serum concentrations necessary for clinical improvement? Time to re-evaluate the therapeutic reference range of venlafaxine

M Scherf-Clavel, L Hommers, C Wurst… - Journal of …, 2020 - journals.sagepub.com
Background: The therapeutic reference range for venlafaxine in antidepressant treatment
has been defined as 100 to 400 ng/mL. However, in an everyday setting active moiety …