Src family protein kinases (SFKs) play a key role in cell adhesion, invasion, proliferation,
survival, apoptosis, and angiogenesis during tumor development. In humans, SFKs consists …

As an evolutionarily conserved intracellular degradation pathway, autophagy is essential to
cellular homeostasis. Several studies have demonstrated that autophagy showed an …

Abstract Background N 6-methyladenosine (m6A) is the most common and abundant
internal modification of RNA. Its critical functions in multiple physiological and pathological …

Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease of unknown origin
that usually results in death from secondary respiratory failure within 2–5 years of diagnosis …

Src family kinases (SFKs) is a non-receptor protein tyrosine kinases family. They are crucial
in signal transduction and regulation of various cell biological processes, such as …

Silicosis is a kind of irreversible pulmonary fibrosis induced by the long-term inhalation of
silica particles. The therapeutic strategy based on the microRNAs might be an effective way …

Gastric cancer is one of the most lethal cancers worldwide. FYN, a gene that is differentially
expressed in gastric cancer, is considered a critical metastasis regulator in several solid …

Fibrosis, a major cause of morbidity and mortality, is a histopathological manifestation of
many chronic inflammatory diseases affecting different systems of the human body. Two …

Silicosis caused by long-term inhalation of crystalline silica during occupational activities
seriously threatens the health of occupational populations. Imbalances in T helper 1 (Th1) …

The aim of the present study was to investigate the anti‑fibrotic effects of astragaloside IV
(ASV) in silicosis rats, and to further explore the potential underlying molecular mechanisms …