Transfusion strategies for hemostatic blood products in critically ill children: a narrative review and update on expert consensus guidelines

SL Valentine, JM Cholette, SM Goobie - Anesthesia & Analgesia, 2022 - journals.lww.com
Critically ill children commonly receive coagulant products (plasma and/or platelet
transfusions) to prevent or treat hemorrhage or correct coagulopathy. Unique aspects of …

Anticoagulation and hemostasis on extracorporeal membrane oxygenation

C Carmona, ME Nellis, O Karam - Current Opinion in Pediatrics, 2023 - journals.lww.com
Most patients on ECMO will develop either a hemorrhagic or thrombotic complication.
Balancing these risks involves careful titration of anticoagulation to prevent clotting and …

Gastrointestinal dysfunction criteria in critically ill children: the PODIUM consensus conference

KV Typpo, SY Irving, JM Prince, N Pathan… - Pediatrics, 2022 - publications.aap.org
CONTEXT Prior criteria to define pediatric multiple organ dysfunction syndrome (MODS) did
not include gastrointestinal dysfunction. OBJECTIVES Our objective was to evaluate current …

Plasma and platelet transfusions strategies in neonates and children undergoing cardiac surgery with cardiopulmonary bypass or neonates and children supported by …

JM Cholette, JA Muszynski, JC Ibla… - Pediatric Critical Care …, 2022 - journals.lww.com
Objectives: To present the recommendations and consensus statements with supporting
literature for plasma and platelet transfusions in critically ill neonates and children …

Bleeding assessment scale in critically ill children (BASIC): physician-driven diagnostic criteria for bleeding severity

ME Nellis, M Tucci, J Lacroix, PC Spinella… - Critical care …, 2019 - journals.lww.com
Objective: Although bleeding frequently occurs in critical illness, no published definition to
date describes the severity of bleeding accurately in critically ill children. We sought to …

Epidemiology of the use of hemostatic agents in children supported by extracorporeal membrane oxygenation: A Pediatric Health Information System Database Study

ME Nellis, LV Vasovic, R Goel, O Karam - Frontiers in pediatrics, 2021 - frontiersin.org
Objectives: Children supported by extracorporeal membrane oxygenation (ECMO) are at
high risk of bleeding. Though practitioners often prescribe blood components and/or …

Epidemiology of hemostatic transfusions in children supported by extracorporeal membrane oxygenation

O Karam, R Goel, H Dalton, ME Nellis - Critical care medicine, 2020 - journals.lww.com
Objective: To evaluate the epidemiology of hemostatic transfusions (plasma, platelet, and
cryoprecipitate) in children supported by extracorporeal membrane oxygenation. Design …

Causes of platelet loss during extracorporeal life support

C Atchison, A Widdershins, WL Chandler - Artificial Organs, 2023 - Wiley Online Library
Background Most pediatric patients show a decline in platelet counts while on
extracorporeal life support (ECLS) and require multiple platelet transfusions. To better …

The use of hemostatic blood products in children following cardiopulmonary bypass and associated outcomes

R Closson, E Mauer, A Stock, JD Dayton… - Critical care …, 2020 - journals.lww.com
Objectives: To describe the use of hemostatic transfusions in children following cardiac
surgery with cardiopulmonary bypass and the association of hemostatic transfusions …

Causes of red blood cell loss during extracorporeal membrane oxygenation

KS Bilodeau, NH Saifee, WL Chandler - Transfusion, 2023 - Wiley Online Library
Background Pediatric patients on extracorporeal membrane oxygenation (ECMO) often
receive repeated red blood cell (RBC) transfusions. This study aims to quantify and …