The role of microRNAs in inflammation

K Das, LVM Rao - International Journal of Molecular Sciences, 2022 - mdpi.com
Inflammation is a biological response of the immune system to various insults, such as
pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro …

Piwi-interacting RNAs (piRNAs) as potential biomarkers and therapeutic targets for cardiovascular diseases

M Li, Y Yang, Z Wang, T Zong, X Fu, LHH Aung… - Angiogenesis, 2021 - Springer
Cardiovascular diseases (CVDs) are the leading causes of death worldwide. Increasing
reports demonstrated that non-coding RNAs (ncRNAs) have been crucially involved in the …

[HTML][HTML] Bat pluripotent stem cells reveal unusual entanglement between host and viruses

M Déjosez, A Marin, GM Hughes, AE Morales… - Cell, 2023 - cell.com
Bats are distinctive among mammals due to their ability to fly, use laryngeal echolocation,
and tolerate viruses. However, there are currently no reliable cellular models for studying bat …

Non-retroviral endogenous viral element limits cognate virus replication in Aedes aegypti ovaries

Y Suzuki, A Baidaliuk, P Miesen, L Frangeul, AB Crist… - Current Biology, 2020 - cell.com
Endogenous viral elements (EVEs) are viral sequences integrated in host genomes. A large
number of non-retroviral EVEs was recently detected in Aedes mosquito genomes, leading …

RNA silencing: From discovery and elucidation to application and perspectives

JH Zhao, HS Guo - Journal of integrative plant biology, 2022 - Wiley Online Library
RNA silencing (or RNA interference, RNAi) is a conserved mechanism for regulating gene
expression in eukaryotes. The discovery of natural trans‐kingdom RNAi indicated that small …

Mammalian antiviral systems directed by small RNA

T Takahashi, SM Heaton, NF Parrish - PLoS pathogens, 2021 - journals.plos.org
There are strong incentives for human populations to develop antiviral systems. Similarly,
genomes that encode antiviral systems have had strong selective advantages. Protein …

Potential utility of melatonin in deadly infectious diseases related to the overreaction of innate immune response and destructive inflammation: focus on COVID-19

DX Tan, R Hardeland - Melatonin Research, 2020 - melatonin-research.net
The high mortality of deadly virus infectious diseases including SARS, MERS, COVID-19,
and avian flu is often caused by the uncontrolled innate immune response and destructive …

Population genomics in the arboviral vector Aedes aegypti reveals the genomic architecture and evolution of endogenous viral elements

CM Crava, FS Varghese, E Pischedda… - Molecular …, 2021 - Wiley Online Library
Horizontal gene transfer from viruses to eukaryotic cells is a pervasive phenomenon.
Somatic viral integrations are linked to persistent viral infection whereas integrations into …

A review of discovery profiling of PIWI-interacting RNAs and their diverse functions in metazoans

S Huang, K Yoshitake, S Asakawa - International Journal of Molecular …, 2021 - mdpi.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs (sncRNAs) that
perform crucial biological functions in metazoans and defend against transposable elements …

Comparative analysis of genome-encoded viral sequences reveals the evolutionary history of flavivirids (family Flaviviridae)

CGG Bamford, WM de Souza, R Parry… - Virus …, 2022 - academic.oup.com
Flavivirids (family Flaviviridae) are a group of positive-strand ribonucleic acid (RNA) viruses
that pose serious risks to human and animal health on a global scale. Here, we use flavivirid …