Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …

Leukemia stem cells (LSCs) have the capacity to self-renew and propagate disease upon
serial transplantation in animal models, and elimination of this cell population is required for …

Circadian clocks are cell-autonomous timing mechanisms that organize cell functions in a
24-h periodicity. In mammals, the main circadian oscillator consists of transcription …

Many aspects of human health and disease display daily rhythmicity. The brain's
suprachiasmic nucleus, which interprets recurring external stimuli, and autonomous …

Acute sleep deprivation is a common condition in modern life and increases anxiety
symptoms in healthy individuals. The neuroinflammatory response induced by microglial …

It is widely recognized that inadequate sleep is associated with multiple acute and chronic
diseases and results in increased mortality and morbidity for cardiovascular diseases. In …

Twenty-four-hour rhythms in immune parameters and functions are robustly observed
phenomena in biomedicine. Here, we summarize the important role of sleep and associated …

Acute respiratory distress syndrome (ARDS) results from overwhelming pulmonary
inflammation. Prior bulk RNA sequencing provided limited insights into ARDS pathogenesis …

Background: Disruption of rhythms in activity and rest occur in many diseases, and provide
an important indicator of healthy physiology and behaviour. However, outside the field of …