[HTML][HTML] Endocannabinoid-mediated control of synaptic transmission
M Kano, T Ohno-Shosaku… - Physiological …, 2009 - journals.physiology.org
The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
Striatal plasticity and basal ganglia circuit function
AC Kreitzer, RC Malenka - Neuron, 2008 - cell.com
The dorsal striatum, which consists of the caudate and putamen, is the gateway to the basal
ganglia. It receives convergent excitatory afferents from cortex and thalamus and forms the …
ganglia. It receives convergent excitatory afferents from cortex and thalamus and forms the …
[HTML][HTML] Selective activation of cholinergic interneurons enhances accumbal phasic dopamine release: setting the tone for reward processing
Dopamine plays a critical role in motor control, addiction, and reward-seeking behaviors,
and its release dynamics have traditionally been linked to changes in midbrain dopamine …
and its release dynamics have traditionally been linked to changes in midbrain dopamine …
Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine
Acetylcholinesterase is one of the most prominent constituents of central cholinergic
pathways. It terminates the synaptic action of acetylcholine through hydrolysis and yields the …
pathways. It terminates the synaptic action of acetylcholine through hydrolysis and yields the …
Physiology and pharmacology of striatal neurons
AC Kreitzer - Annual review of neuroscience, 2009 - annualreviews.org
The basal ganglia occupy the core of the forebrain and consist of evolutionarily conserved
motor nuclei that form recurrent circuits critical for motivation and motor planning. The …
motor nuclei that form recurrent circuits critical for motivation and motor planning. The …
Corticostriatal-hypothalamic circuitry and food motivation: integration of energy, action and reward
Work over the past decade has supported the idea that discrete aspects of appetitive
motivation are differentially mediated by separate but interacting neurochemical systems …
motivation are differentially mediated by separate but interacting neurochemical systems …
Biomarkers of postoperative delirium and cognitive dysfunction
A Fournier, R Krause, G Winterer… - Frontiers in aging …, 2015 - frontiersin.org
Elderly surgical patients frequently experience postoperative delirium (POD) and the
subsequent development of postoperative cognitive dysfunction (POCD). Clinical features …
subsequent development of postoperative cognitive dysfunction (POCD). Clinical features …
M4 muscarinic receptor signaling ameliorates striatal plasticity deficits in models of L-DOPA-induced dyskinesia
A balanced interaction between dopaminergic and cholinergic signaling in the striatum is
critical to goal-directed behavior. But how this interaction modulates corticostriatal synaptic …
critical to goal-directed behavior. But how this interaction modulates corticostriatal synaptic …
The thalamostriatal pathway and cholinergic control of goal-directed action: interlacing new with existing learning in the striatum
The capacity for goal-directed action depends on encoding specific action-outcome
associations, a learning process mediated by the posterior dorsomedial striatum (pDMS). In …
associations, a learning process mediated by the posterior dorsomedial striatum (pDMS). In …
Striatal cholinergic interneuron regulation and circuit effects
The striatum plays a central role in motor control and motor learning. Appropriate responses
to environmental stimuli, including pursuit of reward or avoidance of aversive experience all …
to environmental stimuli, including pursuit of reward or avoidance of aversive experience all …