Efficacy of a high-dose antiresorptive drug holiday to reduce the risk of medication-related osteonecrosis of the jaw (MRONJ): A systematic review

C Ottesen, M Schiodt, K Gotfredsen - Heliyon, 2020 - cell.com
A temporary discontinuation (drug holiday) of high-dose antiresorptive (AR) agents has
been proposed to reduce the risk of medication-related osteonecrosis of the jaw (MRONJ) …

Bisphosphonate-related osteonecrosis of the jaws–a review

S Kühl, C Walter, S Acham, R Pfeffer, JT Lambrecht - Oral oncology, 2012 - Elsevier
The aim was to evaluate the knowledge about bisphosphonate-related osteonecrosis of the
jaws (BRONJ). A bibliographic search in Medline, PubMed and the Cochrane Register of …

Bisphosphonate osteonecrosis of the jaw: a historical and contemporary review

NMH McLeod, PA Brennan, SL Ruggiero - The surgeon, 2012 - Elsevier
The use of bisphosphonate drugs has been popularised in the late 20th century for the
management of many conditions associated with abnormalities of bone turnover, particularly …

Bisphosphonate osteonecrosis of the jaw—a literature review of UK policies versus international policies on bisphosphonates, risk factors and prevention

V Patel, NMH McLeod, SN Rogers… - British Journal of Oral and …, 2011 - Elsevier
There has been an exponential rise in the literature of osteonecrosis and its complications in
patients taking bisphosphonate drugs. Despite this increase, there is little evidence-based …

18 years of medication-related osteonecrosis of the jaw (Mronj) research: Where are we now?—An umbrella review

R Sacco, MD Calasans-Maia, J Woolley, O Akintola… - Applied Sciences, 2021 - mdpi.com
Background: Osteonecrosis of the jaw (ONJ) is a condition affecting patients exposed to
medications used to treat benign and malignant conditions of bone tissue. Many studies …

A Comprehensive Quality Meta-Review of Genetic and Pharmacogenomic Aspects of Medication-Related Osteonecrosis of The Jaw (MRONJ)

R Sacco, S Olate, MD Calasans-Maia, N Sacco… - Applied Sciences, 2022 - mdpi.com
Background: Antiresorptive and antiangiogenic medications can cause a serious adverse
effect known as medication-related osteonecrosis of the jaw (MRONJ). In recent years, a …

Bisphosphonate osteonecrosis (BON): unanswered questions and research possibilities

CA Migliorati, MM Schubert… - Reviews on Recent …, 2009 - ingentaconnect.com
Bisphosphonate osteonecrosis (BON) is a relatively recent adverse drug event that affects
the oral cavity almost exclusively. It has been reported in individuals with metastatic breast …

Pilot study in France about the infiltration of local anaesthetics associated to oral surgery procedures performed under general anaesthesia

C De Verbizier, F Denis, S Moussa-Badran… - Journal of Oral …, 2019 - jomos.org
Introduction: Opinions differ regarding the combined use of local anaesthesia (LA) and
general anaesthesia (GA) in oral surgery procedures. The aim of this study was to evaluate …

Risk reduction strategies for patients at risk of medication-related osteonecrosis of the jaws undergoing dental extractions

R Sacco - 2024 - discovery.ucl.ac.uk
In 2003, a case of osteonecrosis of the jaw related with medicine was documented for the
first time. In the past, osteonecrosis of the jaw was thought to be caused by intravenous and …

[HTML][HTML] Osteoradionecrosis in face: pathophysiology, diagnosis and treatment

J Aldunate, P Coltro, F Busnardo, M Ferreira - Revista Brasileira de …, 2001 - rbcp.org.br
Osteoradionecrosis is one of the most severe complications from radiotherapy used for
treatment of head and neck cancer. It is a disease in which irradiated bone become necrotic …