Alterations in gene sequences, expression levels and protein structure or function have
been associated with every type of cancer. These'molecular markers' can be useful in …

PURPOSE: Many advances have occurred during the last decade in the clinical use of
prostate specific antigen (PSA) for detecting, staging and monitoring prostate cancer. We …

We have developed a novel method, termed loop-mediated isothermal amplification
(LAMP), that amplifies DNA with high specificity, efficiency and rapidity under isothermal …

Continued elucidation of the genetic changes that drive cancer progression is yielding new
and potentially powerful nucleic acid–based markers of neoplastic disease. Pilot studies …

BACKGROUND Most cancer detection tests currently performed are based on either
antibody assays to a marker protein with altered expression in cancer patients or on imaging …

PURPOSE This study was designed to evaluate the potential of reverse-transcriptase
polymerase chain reaction (RT-PCR) analyses for the detection of micrometastatic …

At present, a radical shift in cancer treatment is occurring in terms of predictive, preventive,
and personalized medicine (PPPM). Individual patients will participate in more aspects of …

Histological, immunological, and molecular methods have been used for detecting
micrometastases from nonhematopoietic malignancies. Early studies utilizing cytological …

This invention relates to the use of tumor-derived or asso ciated extracellular ribonucleic
acid (RNA) found circulat ing in the plasma or Serum fraction of blood for the detection …

This invention relates to the use of tumor-derived or asso ciated extracellular ribonucleic
acid (RNA) found circulat ing in the plasma or Serum fraction of blood for the detection …