The NFE2L2 gene encodes the transcription factor Nrf2 best known for regulating the
expression of antioxidant and detoxification genes. Gene knockout approaches have …

Neurodegenerative diseases, cardiovascular disease (CVD), hypertension, insulin
resistance, cancer, and other degenerative processes commonly appear with aging. Ginkgo …

Background Consumption of natural products has increased significantly due to the idea that
if nutrition improves, this leads to improved health, general well-being and reduces the risk …

Inflammation represents a very frequent condition in humans; it is often underestimated,
making the problem an increasingly alarming phenomenon. For these reasons …

Allium species are revered worldwide as vegetables, condiments, and spices as well as the
therapeutic agents in traditional medicine. The bioactive compounds in alliums mainly …

Exposure to microgravity and ionizing radiation during spaceflight missions causes
excessive reactive oxygen species (ROS) production that contributes to cellular stress and …

Abstract Sestrin2 (SESN2), a highly conserved stress-responsive protein, can be triggered
by various noxious stimuli, such as hypoxia, DNA damage, oxidative stress, endoplasmic …

Betanin is a red pigment present in red beetroot. Recently, potential health benefits of
betanin-rich beetroot have been suggested. However, little is known regarding the free …

Neurodegenerative diseases are one of the leading causes of disability and death
worldwide. Intracellular transduction pathways that end in the activation of specific …

The role of phytochemicals as potential prodrugs or therapeutic substances against tumors
has come in the spotlight in the very recent years, thanks to the huge mass of encouraging …