Mitochondria as a therapeutic target for cardiac ischemia‑reperfusion injury

W Marin, D Marin, X Ao, Y Liu - … Journal of Molecular …, 2021 - spandidos-publications.com
Acute myocardial infarction is the leading cause of cardiovascular‑related mortality and
chronic heart failure worldwide. As regards treatment, the reperfusion of ischemic tissue …

Inhibition of Pyruvate kinase M2 (PKM2) by shikonin attenuates isoproterenol-induced acute myocardial infarction via reduction in inflammation, hypoxia, apoptosis …

M Rihan, SS Sharma - Naunyn-Schmiedeberg's Archives of Pharmacology, 2024 - Springer
Myocardial infarction (MI) is a major cause of mortality and disability globally. MI results from
acute or chronic myocardial ischemia characterized by an imbalance of oxygen demand and …

Cardioprotective role of scopoletin on isoproterenol-induced myocardial infarction in rats

N Rong, R Yang, IAA Ibrahim, W Zhang - Applied Biochemistry and …, 2023 - Springer
Scopoletin is a phenolic coumarin isolated from a variety of plants and was originally used to
treat various diseases including arthritis as well as bone-related diseases. The goal of this …

[HTML][HTML] In an experimental myocardial infarction model, L-arginine pre-intervention may exert cardioprotective effects by regulating OTULIN levels and mitochondrial …

S Kaya, T Yalcın - Cell Stress and Chaperones, 2023 - Elsevier
The experimental myocardial infarction (MI) model originating from isoproterenol (ISO) is
frequently preferred in research due to its similarity to MI-induced damage in humans …

Polycyclic aromatic hydrocarbon exposure and atherosclerotic cardiovascular disease risk in urban adults: The mediating role of oxidatively damaged DNA

L Cao, D Wang, C Zhu, B Wang, X Cen, A Chen… - Environmental …, 2020 - Elsevier
Polycyclic aromatic hydrocarbon (PAH) exposure has been considered a risk factor for
cardiovascular diseases (CVD), whereas possible mechanisms for this association have not …

BYD ameliorates oxidative stress-induced myocardial apoptosis in heart failure post-acute myocardial infarction via the P38 MAPK-CRYAB signaling pathway

Y Zhang, C Li, H Meng, D Guo, Q Zhang, W Lu… - Frontiers in …, 2018 - frontiersin.org
Aim: Heart failure (HF) post-acute myocardial infarction (AMI) contributes to increasing
mortality and morbidity worldwide. Baoyuan decoction (BYD) is a well-known traditional …

Prognostic value of oxidative stress in patients with acute myocardial infarction complicated by cardiogenic shock: A prospective cohort study

M Tomandlova, J Parenica, P Lokaj, T Ondrus… - Free Radical Biology …, 2021 - Elsevier
Introduction Cardiogenic shock is a frequent complication of acute myocardial infarction.
Similar to ischemia/reperfusion injury, excessive production of reactive oxygen species can …

Huoxin pill prevents acute myocardial ischaemia injury via inhibition of Wnt/β‑catenin signaling

Q Wang, E Ma, D Wo, J Chen, J He… - Journal of Cellular …, 2021 - Wiley Online Library
Myocardial infarction (MI) is one of the leading causes of death worldwide, and due to the
widespread and irreversible damage caused, new therapeutic treatments are urgently …

TRIM21 aggravates cardiac injury after myocardial infarction by promoting M1 macrophage polarization

Z Li, X Liu, X Zhang, W Zhang, M Gong, X Qin… - Frontiers in …, 2022 - frontiersin.org
Macrophage polarization followed by myocardial infarction (MI) is essential for wound
healing. Tripartite motif-containing protein 21 (TRIM21), a member of E3 ubiquitin ligases, is …

[HTML][HTML] Chaihujialonggumulitang shows psycho-cardiology therapeutic effect on acute myocardial infarction with comorbid anxiety by the activation of Nrf2/HO-1 …

J Shi, J Hou, Y Sun, Z Jia, Y Zhou, C Wang… - Biomedicine & …, 2022 - Elsevier
Background Anxiety is a common comorbidity of cardiovascular diseases, which
deteriorated cardiac function. Chaihujialonggumulitang (BFG) was reported to have …