Hypofunction of N-methyl-d-aspartic acid-type glutamate receptors (NMDAR) induced by the
systemic administration of NMDAR antagonists is well known to cause schizophrenia-like …

Connections between neurons are affected within 3 min of stroke onset by massive ischemic
depolarization and then delayed cell death. Some connections can recover with prompt …

TREK‐1 is a two‐pore‐domain background potassium channel expressed throughout the
central nervous system. It is opened by polyunsaturated fatty acids and lysophospholipids. It …

Major depression is a prevalent emotion disorder. Chronic stressful life in genetically
susceptible individuals is presumably a major etiology that leads to neuron and synapse …

Stroke may cause severe death and disability but many clinical trials have failed in the past,
partially because the lack of an effective method to regenerate new neurons after stroke. In …

Background and Purpose—The purpose of this research was to investigate the impact of
lesion location on motor excitability and motor performance. Methods—We studied patients …

Ischemic stroke is a serious public health problem worldwide. Here, we characterized the
metabolite features of acute ischemic stroke (AIS) using a gas chromatography-mass …

Cortical compression can be a significant problem in many types of brain injuries, such as
brain trauma, localized brain edema, hematoma, focal cerebral ischemia, or brain tumors …

Background Major depression, persistent low mood, is one of common psychiatric diseases.
Chronic stressful life is believed to be a major risk factor that leads to dysfunctions of the …

Traumatic brain injury (TBI) can result in persistent sensorimotor and cognitive deficits
including long-term altered sensory processing. The few animal models of sensory cortical …