Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Vascular smooth muscle cells (VSMCs) are the fundamental component of the medial layer
of arteries and are essential for arterial physiology and pathology. It is becoming …

Despite the dramatic improvements of revascularization therapies occurring in the past
decades, a relevant percentage of patients treated with percutaneous coronary intervention …

The coronary angiogram is the gold standard for evaluating the severity of coronary artery
disease stenoses. Presently, the assessment is conducted visually by cardiologists, a …

The critical role of the coronary microvascular compartment and its invasive functional
assessment has become apparent in light of the significant proportion of patients presenting …

Atherosclerosis-related coronary artery disease (CAD) is one of the leading sources of
mortality and morbidity in the world. Primary and secondary prevention appear crucial to …

Type-2 diabetes mellitus (DM) represents one of the most important risk factors for
cardiovascular diseases (CVD). Hyperglycemia and glycemic variability are not the only …

Surgical myocardial revascularization is associated with long-term survival benefit in
patients with multivessel coronary artery disease. However, the exact biological …

Atherosclerosis is an underlying risk factor in cardiovascular diseases (CVDs). The
combination of drugs with microRNAs (miRNA) inside a single nanocarrier has emerged as …

Endothelin is a chemical mediator that helps in maintaining balance within the blood‐brain
barrier by regulating the levels of toxicants and molecules which pass through the brain …